Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Novel findings in inhibition of mast cell-dependent immediate-type cutaneous reactions by Gahmi-Shini-San
Autore:
Hong, SH; Kim, MS; Lee, JY; Hwang, CY; Baek, SH; Han, DS; Jung, WY; Seo, SB; Kajiuchi, T; Kim, HM;
Indirizzi:
Wonkwang Univ, Dept Oriental Pharm, Coll Pharm, Iksan 570749, Chonbuk, South Korea Wonkwang Univ Iksan Chonbuk South Korea 570749 0749, Chonbuk, South Korea Wonkwang Univ, Ctr Oriental Med Sci, Iksan 570749, Chonbuk, South Korea Wonkwang Univ Iksan Chonbuk South Korea 570749 0749, Chonbuk, South Korea Wonkwang Univ, Coll Oriental Med, Iksan 570749, Chonbuk, South Korea Wonkwang Univ Iksan Chonbuk South Korea 570749 0749, Chonbuk, South Korea Wonkwang Univ, Dept Nat Prod, Profess Grad Sch Oriental Med, Iksan 570749,Chonbuk, South Korea Wonkwang Univ Iksan Chonbuk South Korea 570749 70749,Chonbuk, South Korea Wonkwang Univ, Dept Oral Anat, Sch Dent, Iksan 570749, Chonbuk, South Korea Wonkwang Univ Iksan Chonbuk South Korea 570749 0749, Chonbuk, South Korea JAKWANG Co Ltd, Ansung 456380, Kyonggi, South Korea JAKWANG Co Ltd AnsungKyonggi South Korea 456380 80, Kyonggi, South Korea Tokyo Inst Technol, Dept Int Dev Engn, Meguro Ku, Tokyo 1528552, Japan Tokyo Inst Technol Tokyo Japan 1528552 , Meguro Ku, Tokyo 1528552, Japan
Titolo Testata:
CLINICA CHIMICA ACTA
fascicolo: 1, volume: 309, anno: 2001,
pagine: 85 - 90
SICI:
0009-8981(20010705)309:1<85:NFIIOM>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALLERGIC REACTIONS; HISTAMINE-RELEASE; HIGH-AFFINITY; RATS; IGE; COMPOUND-48/80; ANAPHYLAXIS; RECEPTOR; SUBUNIT; CALCIUM;
Keywords:
Gahmi-Shini-San; rat peritoneal mast cells; alcian blue/nuclear fast red staining; ear swelling response; passive cutaneous anaphylaxis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, HM Wonkwang Univ, Dept Oriental Pharm, Coll Pharm, Iksan 570749, Chonbuk, South Korea Wonkwang Univ Iksan Chonbuk South Korea 570749 onbuk, South Korea
Citazione:
S.H. Hong et al., "Novel findings in inhibition of mast cell-dependent immediate-type cutaneous reactions by Gahmi-Shini-San", CLIN CHIM A, 309(1), 2001, pp. 85-90

Abstract

This report describes an inhibitory effect of Gahmi-Shini-San (GSS) on mast cell-mediated immediate-type allergic reactions. GSS is an Oriental herbal medication, which has been successfully used in Korea for the treatment of allergic disorders, mainly skin anaphylactic diseases. GSS inhibited the ear swelling response induced by intradermal injection of compound 48/80 ina mouse model on a concentration-dependent basis. The mast cells in mouse ear tissue were stained by alcian blue/nuclear fast led. GSS significantly inhibited the compound 48/80-induced degranulation from mast cells in ear tissue. GSS dose-dependently inhibited the histamine release from the rat peritoneal mast cells by compound 48/80. We also studied the effect of GSS onmast cell-dependent passive cutaneous anaphylaxis activated by dinitrophenyl IgE antibody. GSS showed inhibition of passive cutaneous anaphylaxis following oral administration. These results indicated that GSS has inhibitoryeffect on mast cell-dependent immediate type cutaneous reactions. (C) 2001Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 01:47:13