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Titolo:
Heart rate variability in ischemic heart disease
Autore:
Huikuri, HV; Makikallio, TH;
Indirizzi:
Univ Oulu, Dept Med, Div Cardiol, Oulu 90220, Finland Univ Oulu Oulu Finland 90220 Dept Med, Div Cardiol, Oulu 90220, Finland
Titolo Testata:
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
fascicolo: 1-2, volume: 90, anno: 2001,
pagine: 95 - 101
SICI:
1566-0702(20010720)90:1-2<95:HRVIIH>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; FREQUENCY-DOMAIN MEASURES; CORONARY-ARTERY DISEASE; SYMPATHETIC-NERVE ACTIVITY; LEFT-VENTRICULAR FUNCTION; RATE DYNAMICS; INTERVAL DYNAMICS; SPECTRAL COMPONENTS; PERIOD VARIABILITY; SPONTANEOUS ONSET;
Keywords:
autonomic nervous system; coronary artery disease;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Huikuri, HV Univ Oulu, Dept Med, Div Cardiol, Kajaanintie 50, Oulu 90220, Finland Univ Oulu Kajaanintie 50 Oulu Finland 90220 lu 90220, Finland
Citazione:
H.V. Huikuri e T.H. Makikallio, "Heart rate variability in ischemic heart disease", AUTON NEURO, 90(1-2), 2001, pp. 95-101

Abstract

Major untoward events, such as life-threatening arrhythmias and acute coronary events, have been suggested to be triggered by the activation of the autonomic nervous system in patients with coronary artery disease. Analysis of heart rate variability by conventional time and frequency domain methods, as well as by newer methods derived from nonlinear system theory, has offered a novel approach for studying the abnormalities in cardiovascular neural regulation in ischemic heart disease. Heart rate variability has been shown to be altered among patients with ischemic heart disease as compared totheir age-matched controls without the evidence of ischemic heart disease. There are also obvious differences in various measures of heart rate variability between patients with uncomplicated coronary artery disease and these with coronary artery disease with complicated myocardial infarction. Impaired high-frequency oscillations of heart rate is the most prominent feature in patients with uncomplicated coronary artery disease, suggesting mainlyan impairment in vagal autonomic regulation. Patients with prior myocardial infarction have a reduced overall heart rate variability, and a specific spectral pattern with a reduced low-frequency spectral component has been observed in patients with prior myocardial infarction and impaired left ventricular function. Recent studies have shown that the new nonlinear measures, particularly fractal analysis methods of heart rate dynamics, can detect subtle changes in heart rate behavior that are not easily detected by traditional analysis methods from ambulatory recordings. Patients with prior myocardial infarction have steeper power-law slope analyzed from the ultra andvery low-frequency spectral bands, and they also have more random short-term heart rate dynamics analyzed by the detrended fluctuation method. A large body of data indicate that reduced overall heart rate variability is associated with an increased risk of mortality and nonfatal cardiac events in patient with ischemic heart disease. Of particular note, recent studies indicate that fractal analysis methods perform even better than the traditionalanalysis methods of heart rate variability as predictors of death and the onset of life-threatening arrhythmic events in post-infarction populations. These findings support the notion that heart rate variability analysis methods, such as fractal and complexity measures as well as conventional techniques, give valuable clinical information among patients with ischemic heart disease. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 21:59:22