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Titolo:
RR-arterial pressure variability relationships
Autore:
Baselli, G; Porta, A; Cerutti, S; Caiani, EG; Lucini, D; Pagani, M;
Indirizzi:
Politecn Milan, Dipartimento Bioingn, I-20133 Milan, Italy Politecn MilanMilan Italy I-20133 timento Bioingn, I-20133 Milan, Italy Univ Milan, Dipartimento Sci Preclin, LITA Vialba, Milan, Italy Univ Milan Milan Italy artimento Sci Preclin, LITA Vialba, Milan, Italy Univ Milan, Osped L Sacco, Milan, Italy Univ Milan Milan ItalyUniv Milan, Osped L Sacco, Milan, Italy
Titolo Testata:
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
fascicolo: 1-2, volume: 90, anno: 2001,
pagine: 57 - 65
SICI:
1566-0702(20010720)90:1-2<57:RPVR>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-RATE-VARIABILITY; BLOOD-PRESSURE; CONSCIOUS DOGS; RESPIRATION; MODEL; IDENTIFICATION; CIRCULATION; RECORDINGS; SIGNALS;
Keywords:
cardiovascular variability; closed-loop identification; mayer waves; baroreflex; cardiopulmonary reflexes;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Baselli, G Politecn Milan, Dipartimento Bioingn, Piazza Leonardo da Vinci 32, I-20133Milan, Italy Politecn Milan Piazza Leonardo da Vinci 32 Milan Italy I-20133
Citazione:
G. Baselli et al., "RR-arterial pressure variability relationships", AUTON NEURO, 90(1-2), 2001, pp. 57-65

Abstract

Methodological aspects of a causal black-box model of heart period/arterial pressure interaction, arterial pressure closed-loop regulation and respiration effects on both heart period and arterial pressure are revisited in the "time" (more exactly heart beat count) domain. Parameters are estimated from experimental data (model identification) by means of multiple linear regressions of actual samples over the past ones. The elements composing either heart period or systolic arterial pressure variability are visualised as beat-by-beat series. Indexes describing the signal interactions, the loopproperties and the spectral components of the variability series are consequently summarised. In 17 normal young volunteers, the analysis was carried out during active standing, rest, mild clinostatic pedalling exercise at 10%, 20%, and 30% ofthe maximum effort, and recovery. A negative effect of heart period changes on systolic arterial pressure of - 13.3 mm Hg/s was found at rest. This effect, though augmented by exercise, appeared insignificant in explaining arterial pressure variability. Arterial baroreflex was assessed by alpha (art) index which had a value of 5.18 mm Hg/ms at rest, 3.78 mm Hg/ms during active standing, and decreased progressively with exercise down to 0.55 mmHg/ms. The pressure regulation loop displayed a tendency to amplify disturbances at low frequency (around 0.1 Hz) 5.94 times at rest, augmented to 8.88 rimes during standing, 7.55 at 30% exercise. The first parameter of the pressure auto-regression was slightly higher than 1 at rest and even more augmented during standing, thus, indicating a tendency of arterial pressure perturbations to persist from one beat to the next. These mechanisms appear important in the genesis of low-frequency pressure waves. Nonetheless, the trace of different sources was evident in the regression residuals. Noticeably, during exercise it explained 10.16% of total heart period variability compared to 12.49% related to the low-frequency oscillations of closed-loops. The origin of high-frequency waves synchronous with respiration appeared miscellaneous as well. Arterial pressure appeared negligibly affected by heart period changes. Conversely, a limited effect of arterial pressure waves was found on heart period superimposed to a large effect of cardiopulmonaryreflexes directly modulating the sinus node. In conclusion, both high-frequency and low-frequency waves are composite phenomena and a multi-channel analysis comparing heart period and arterial pressure variability yields a variety of figures assessing cardiovascular regulation and cardiorespiratory coupling. (C) 2001 Elsevier Science B.V. Allrights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/05/20 alle ore 12:42:03