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Titolo:
Vas deferens, a site of male contraception: an overview
Autore:
Lohiya, NK; Manivannan, B; Mishra, PK; Pathak, N;
Indirizzi:
Univ Rajasthan, Dept Zool, Reprod Physiol Sect, Jaipur 302004, Rajasthan, India Univ Rajasthan Jaipur Rajasthan India 302004 pur 302004, Rajasthan, India
Titolo Testata:
ASIAN JOURNAL OF ANDROLOGY
fascicolo: 2, volume: 3, anno: 2001,
pagine: 87 - 95
SICI:
1008-682X(200106)3:2<87:VDASOM>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESBYTIS-ENTELLUS ENTELLUS; NO-SCALPEL VASECTOMY; LANGUR MONKEYS; ULTRASTRUCTURAL-CHANGES; REPRODUCTIVE EXOCRINE; NONINVASIVE REVERSAL; INTRAVASAL INJECTION; ANTIFERTILITY AGENT; CHEMICAL-AGENTS; SILICONE-RUBBER;
Keywords:
male contraception; vas deferens; vasectomy; vas occlusives; injectable plugs; RISUG(R);
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
93
Recensione:
Indirizzi per estratti:
Indirizzo: Lohiya, NK Univ Rajasthan, Dept Zool, Reprod Physiol Sect, Jaipur 302004, Rajasthan, India Univ Rajasthan Jaipur Rajasthan India 302004 Rajasthan, India
Citazione:
N.K. Lohiya et al., "Vas deferens, a site of male contraception: an overview", ASIAN J AND, 3(2), 2001, pp. 87-95

Abstract

The vas deferens is a site which can be exploited for male contraception without undue side effects. The only effective technique available for male contraception is vasectomy, being practiced world wide, despite that it is a permanent surgical procedure and its successful reversal is not assured. Although no-scalpel vasectomy minimizes surgical procedures, the fate of its reversal is akin to that of vasectomy. Several occlusive and non-occlusive vasal procedures which claim to be reversible without surgical intervention, possess more disadvantages than advantages. Vas occlusion with plug, 'Shug' or medical grade silicone rubber, although claimed to produce reversible azoospermia without affecting spermatogenesis, requires skilled microsurgery for their implantation and later removal. RISUG(R), a non-sclerotic polymer styrene maleic anhydride (SMA), could be more advantageous than vasectomy and other vas occlusive procedures in that it could be a totally non-invasive procedure by "no-scalpel injection" and "non-invasive reversal". Itis claimed to offer long-term contraception without adverse side effects and also to be possible as a male spacing method by repeated vas occlusion and non-invasive reversal. The drug is currently under multicentre Phase m clinical trial.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:31:49