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Titolo:
Transient seizure activity demonstrated by Tc-99m HMPAO SPECT and diffusion-weighted MR imaging
Autore:
Sagiuchi, T; Ishii, K; Asano, Y; Aoki, Y; Woodhams, R; Yanaihara, H; Kan, S; Hayakawa, K;
Indirizzi:
Kitasato Univ, Sch Med, Dept Radiol, Kanagawa 2288555, Japan Kitasato Univ Kanagawa Japan 2288555 ept Radiol, Kanagawa 2288555, Japan
Titolo Testata:
ANNALS OF NUCLEAR MEDICINE
fascicolo: 3, volume: 15, anno: 2001,
pagine: 267 - 270
SICI:
0914-7187(200106)15:3<267:TSADBT>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARTIAL STATUS EPILEPTICUS; EPILEPSY; COEFFICIENT;
Keywords:
seizure activity; epilepsy; diffusion-weighted MR imaging; technetium-99m; hexamethylpropyleneamine oxime (Tc-99m HMPAO); single photon emission computed tomography; (SPECT);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Sagiuchi, T Kitasato Univ, Sch Med, Dept Radiol, 1-15-1 Kitasato, Kanagawa2288555, Japan Kitasato Univ 1-15-1 Kitasato Kanagawa Japan 2288555 5, Japan
Citazione:
T. Sagiuchi et al., "Transient seizure activity demonstrated by Tc-99m HMPAO SPECT and diffusion-weighted MR imaging", ANN NUCL M, 15(3), 2001, pp. 267-270

Abstract

Cerebral perfusion single photon emission computed tomography (SPECT) has been used to confirm the localization of the epileptic focus and the evaluation of seizure. Recently, diffusion-weighted MR imaging (DWI) has been recognized for evaluation of seizure activity. We describe a case of transientseizure activity demonstrated by Tc-99m HMPAO SPECT and DWI. This patient was a 61-year-old woman with a 10-month history of right middle cerebral artery (MCA) infarction who had a generalized seizure during MRI. DWI immediately after seizure showed transient hyperintensity in the right frontal gray matter and the white matter, and these apparent diffusion coefficients (ADC) were transiently decreased. This transient hyperintensity on DWI corresponded to transient hyperperfusion identifying the epileptic focus on interictal Tc-99m HMPAO SPECT. Transient sustained seizure activity might cause these changes on DWI and SPECT. It was considered that interictal Tc-99m HMPAO SPECT showed the delayed hyperperfusion caused by excitatory neuronal overaction and DWI showed cytotoxic edema seizure-induced by energy failure of the membrane-bound Na/K-ATPase pump.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:27:15