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Titolo:
Esophagectomy for squamous cell carcinoma of the esophagus isolated or associated with head and neck cancer: long-term results.
Autore:
Roullet, MH; Wind, P; Zinzindohoue, F; Laccourreye, O; Berger, A; Chevallier, JM; Bonfils, P; Brasnu, D; Cugnenc, PH;
Indirizzi:
Hop Europeen Georges Pompidou, Serv Chirurg Digest, F-75005 Paris, France Hop Europeen Georges Pompidou Paris France F-75005 F-75005 Paris, France Hop Europeen Georges Pompidou, Serv ORL, F-75005 Paris, France Hop Europeen Georges Pompidou Paris France F-75005 F-75005 Paris, France
Titolo Testata:
ANNALES DE CHIRURGIE
fascicolo: 6, volume: 126, anno: 2001,
pagine: 526 - 534
SICI:
0003-3944(200107)126:6<526:EFSCCO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
FRE
Soggetto:
UPPER AERODIGESTIVE TRACT; LUGOL; MALIGNANCIES; PATIENT; TUMORS;
Keywords:
esophageal squamous cell carcinoma; esophagus and head and neck cancer esophagectomy; head and neck cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Roullet, MH Hop Europeen Georges Pompidou, Serv Chirurg Digest, 20 Rue Leblanc, F-75005 Paris, France Hop Europeen Georges Pompidou 20 Rue Leblanc Paris France F-75005
Citazione:
M.H. Roullet et al., "Esophagectomy for squamous cell carcinoma of the esophagus isolated or associated with head and neck cancer: long-term results.", ANN CHIR, 126(6), 2001, pp. 526-534

Abstract

Study aim: Esophageal squamous cell carcinomas are frequently associated with head and neck cancers. This retrospective study was conducted to compare the longterm outcome of the patients with a double cancer and of the patients with a solitary esophageal cancer after curative management. Patients and methods: From 1989 to 1999, 114 patients with an esophageal carcinoma were included in the study. Among them, 52 had an associated head and neck cancer (metachronous: n=17 and synchronous : n=35). Curative treatment was achieved in all patients. The patients were divided in "solitary" and "associated" group. Results: Age, sex distribution, tumor location and histological findings were similar in the two groups. The esophageal resection was an esopharyngolaryngectomy (n=13), a subtotal esophagectomy with cervical anastomosis (n=92) and a Lewis-Santy esophagectomy with thoracic anastomosis (n=9). Operative mortality (8 versus 7.7%), anastomotic leaks rate (14,5 versus 21%) and pneumonia rate (21 versus 9,6%) were not significantly different in the twogroups. The mean hospital stay was 27 days. The mean follow-up was 85 +/- 50 months. Five-year survival rates were not significantly different in thetwo groups (p=0.6411). In univariate survival analysis the only significant predictive factors were the depth of esophageal tumor invasion (p=0.0002)and node involvement (p=0.0373). The presence of head and neck cancer did not affect survival after esophagectomy. Conclusion: With an agressive therapeutic plan, the survival of patients with an esophageal cancer associated to head and neck cancer was similar to the survival of patients with an isolated esophageal carcinoma. Long term esophageal survey seems to be useful to detect more superficial esophageal carcinomas in patients with head and neck cancer. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:57:07