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Titolo:
The state of leukocyte adhesiveness/aggregation in the peripheral blood ofpatients with type 2 diabetes and ischemic vascular disease
Autore:
Fusman, R; Rotstein, R; Zeltser, D; Prochorov, V; Shapira, I; Bornstein, NM; Keren, G; Roth, A; Miller, HI; Avitzour, D; Arber, N; Berliner, S;
Indirizzi:
Ichilov Hosp, Tel Aviv Sourasky Med Ctr, Dept Internal Med D, IL-64239 TelAviv, Israel Ichilov Hosp Tel Aviv Israel IL-64239 al Med D, IL-64239 TelAviv, Israel Tel Aviv Sourasky Med Ctr, Dept Neurol, Tel Aviv, Israel Tel Aviv SouraskyMed Ctr Tel Aviv Israel Dept Neurol, Tel Aviv, Israel Tel Aviv Sourasky Med Ctr, Dept Cardiol, Tel Aviv, Israel Tel Aviv Sourasky Med Ctr Tel Aviv Israel ept Cardiol, Tel Aviv, Israel Tel Aviv Sourasky Med Ctr, Dept Gastroenterol, Tel Aviv, Israel Tel Aviv Sourasky Med Ctr Tel Aviv Israel stroenterol, Tel Aviv, Israel Timorim Technol, Jerusalem, Israel Timorim Technol Jerusalem IsraelTimorim Technol, Jerusalem, Israel
Titolo Testata:
ACTA DIABETOLOGICA
fascicolo: 1, volume: 38, anno: 2001,
pagine: 43 - 49
SICI:
0940-5429(200103)38:1<43:TSOLAI>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
INFLAMMATION METER; ADHESION MOLECULES; ENDOTHELIAL-CELLS; MONOCYTE ADHESION; IN-VITRO; AGGREGATION; EXPRESSION; NEUTROPHIL; INDUCTION; MECHANISM;
Keywords:
leukocyte adhesiveness/aggregation; diabetes mellitus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Berliner, S Ichilov Hosp, Tel Aviv Sourasky Med Ctr, Dept Internal Med D, 6 Weizman St, IL-64239 Tel Aviv, Israel Ichilov Hosp 6 Weizman St Tel AvivIsrael IL-64239 iv, Israel
Citazione:
R. Fusman et al., "The state of leukocyte adhesiveness/aggregation in the peripheral blood ofpatients with type 2 diabetes and ischemic vascular disease", ACT DIABETO, 38(1), 2001, pp. 43-49

Abstract

White blood cells have a potential role in the pathogenesis of vasculopathy in diabetic patients. We studied the circulating peripheral blood in a cohort of patients with documented ischemic heart or brain disease with and without type 2 diabetes by means of image analysis and flow cytometry. Our study showed that the state of leukocyte adhesiveness/aggregation is slightly increased in those who had concomitant diabetes but that there was no difference regarding the expression of CD11b/CD18 and CD62L antigens on the surface of the peripheral blood white blood cells. The finding of a significantly increased number of white blood cells in the peripheral blood of patients with ischemic vascular diseases is important insofar as it is associated with a poorer prognosis.

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Documento generato il 24/11/20 alle ore 13:58:40