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Titolo:
Generation of dendritic cells: role of cytokines and potential clinical applications
Autore:
Syme, R; Gluck, S;
Indirizzi:
Univ Calgary, Fac Med, Dept Oncol, Tom Baker Canc Ctr, Calgary, AB T2N 4N2, Canada Univ Calgary Calgary AB Canada T2N 4N2 c Ctr, Calgary, AB T2N 4N2, Canada Univ Calgary, Fac Med, Dept Med, Tom Baker Canc Ctr, Calgary, AB T2N 4N2, Canada Univ Calgary Calgary AB Canada T2N 4N2 c Ctr, Calgary, AB T2N 4N2, Canada Univ Calgary, Fac Med, Dept Pharmacol & Therapeut, Tom Baker Canc Ctr, Calgary, AB T2N 4N2, Canada Univ Calgary Calgary AB Canada T2N 4N2 c Ctr, Calgary, AB T2N 4N2, Canada
Titolo Testata:
TRANSFUSION AND APHERESIS SCIENCE
fascicolo: 2, volume: 24, anno: 2001,
pagine: 117 - 124
SICI:
1473-0502(200104)24:2<117:GODCRO>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLONY-STIMULATING FACTOR; HEMATOPOIETIC PROGENITOR CELLS; C-KIT LIGAND; NECROSIS-FACTOR-ALPHA; BONE-MARROW CULTURES; MHC CLASS-II; PERIPHERAL-BLOOD; FLT3 LIGAND; TNF-ALPHA; GM-CSF;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Gluck, S Univ Calgary, Fac Med, Dept Oncol, Tom Baker Canc Ctr, 1331 29th St,NW, Calgary, AB T2N 4N2, Canada Univ Calgary 1331 29th St,NW Calgary AB Canada T2N 4N2 N2, Canada
Citazione:
R. Syme e S. Gluck, "Generation of dendritic cells: role of cytokines and potential clinical applications", TRANSF AP S, 24(2), 2001, pp. 117-124

Abstract

Over the last decade there has been great interest in generating populations of antigen presenting cells (APC), which can be exploited to improve immune responses to a variety of diseases including malignancies. Dendritic cells (DC) are an APC population that are easily generated ex vivo using a variety of cytokines. Cytokines can also be used to further manipulate these cells in maturation and function. The following discussion will provide an overview of dendritic cell isolation and generation with a focus on the role cytokines play in this process. (C) 2001 Elsevier Science Ltd. All rightsreserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:39:33