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Titolo:
Comparison of the effects of sleep deprivation, alcohol and obstructive sleep apnoea (OSA) on simulated steering performance
Autore:
Hack, MA; Choi, SJ; Vijayapalan, P; Davies, RJO; Stradling, JR;
Indirizzi:
Oxford Radcliffe Trust, Oxford Ctr Resp Med, Oxford OX3 7LJ, England Oxford Radcliffe Trust Oxford England OX3 7LJ d, Oxford OX3 7LJ, England
Titolo Testata:
RESPIRATORY MEDICINE
fascicolo: 7, volume: 95, anno: 2001,
pagine: 594 - 601
SICI:
0954-6111(200107)95:7<594:COTEOS>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITIVE AIRWAY PRESSURE; PULSE TRANSIT-TIME; ACCIDENTS INVOLVING PATIENTS; PROSPECTIVE PARALLEL TRIAL; AUTOMOBILE ACCIDENTS; APNEA SYNDROME; NASAL CPAP; DRIVING PERFORMANCE; RESPIRATORY EVENTS; DAYTIME SLEEPINESS;
Keywords:
obstructive sleep apnoea; driving; automobile accidents; steering simulation; sleep deprivation; alcohol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Stradling, JR Oxford Radcliffe Trust, Oxford Ctr Resp Med, Churchill Campus, Oxford OX3 7LJ, England Oxford Radcliffe Trust Churchill Campus Oxford England OX3 7LJ
Citazione:
M.A. Hack et al., "Comparison of the effects of sleep deprivation, alcohol and obstructive sleep apnoea (OSA) on simulated steering performance", RESP MED, 95(7), 2001, pp. 594-601

Abstract

Patients with obstructive sleep apnoea (OSA) are reported to have an increased risk of road traffic accidents. This study examines the nature of the impairment during simulated steering in patients with OSA, compared to normal subjects following; either sleep deprivation or alcohol ingestion. Twenty-six patients with OSA and 12 normal subjects, either deprived of one night's sleep or following alcohol ingestion [mean (sD) alcohol blood level 71.6 mg dl(-1) (19.6)], performed a simulated steering task for a total of 90 min. Performance was measured using the tendency to wander (SD), deterioration across the task, number of 'off-road' events and the reaction time to peripheral events. Control data for OSA, sleep deprivation and alcoholwere obtained following treatment with nasal continuous positive airway pressure (nCPAP), after a normal night of sleep, and following no; alcohol, respectively. Patients with untreated OSA, and sleep-deprived or alcohol-intoxicated normal subjects performed significantly less well, compared to their respective controls (P<0.01 for all tests), with untreated OSA lying between that ofalcohol intoxication and sleep deprivation. Alcohol impaired steering error equally throughout the whole drive, whilst sleep deprivation caused progressive deterioration through the drive, but not initially. Untreated OSA was more like sleep deprivation than alcohol, although there was a wide spread of data. This suggests that,the driving impairment in patients with OSA is more compatible with sleep deprivation or fragmentation as the cause, rather than abnormal cognitive or motor skills.

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Documento generato il 23/09/20 alle ore 06:41:41