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Titolo:
Re-186-Etidronate - Efficacy of palliative radionuclide therapy for painful bone metastases
Autore:
Han, SH; De Klerk, JMH; Zonnenberg, BA; Tan, S; Van Rijk, PP;
Indirizzi:
Univ Utrecht, Med Ctr, Dept Nucl Med, Utrecht, Netherlands Univ Utrecht Utrecht Netherlands r, Dept Nucl Med, Utrecht, Netherlands Univ Utrecht, Med Ctr, Dept Internal Med, Oncol Sect, Utrecht, NetherlandsUniv Utrecht Utrecht Netherlands Med, Oncol Sect, Utrecht, Netherlands
Titolo Testata:
QUARTERLY JOURNAL OF NUCLEAR MEDICINE
fascicolo: 1, volume: 45, anno: 2001,
pagine: 84 - 90
SICI:
1125-0135(200103)45:1<84:R-EOPR>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
BREAST-CANCER PATIENTS; OSSEOUS METASTASES; PROSTATE-CANCER; RE-186 HEDP; RADIATION-THERAPY; RHENIUM-186-HEDP; MANAGEMENT; SR-89; RADIOPHARMACEUTICALS; QUESTIONNAIRE;
Keywords:
bone neoplasms, secondary; bone neoplasms, radiotherapy; pain, therapy; rhenium, therapeutic use; radiopharmaceuticals;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Han, SH Univ Utrecht Hosp, Dept Nucl Med, POB 85500, NL-3508 GA Utrecht, Netherlands Univ Utrecht Hosp POB 85500 Utrecht Netherlands NL-3508 GA rlands
Citazione:
S.H. Han et al., "Re-186-Etidronate - Efficacy of palliative radionuclide therapy for painful bone metastases", Q J NUCL M, 45(1), 2001, pp. 84-90

Abstract

Pain palliation with bone-seeking radiopharmaceuticals is an effective treatment modality in patients with advanced metastatic bone cancer. Several studies have shown encouraging clinical results of palliative therapy using Re-186-HEDP, with an overall reported response rate of +/- 71% for painful osseous metastasized prostate and breast cancer patients. Re-186-HEDP is a very potential isotope with numerous advantageous characteristics for this purpose. Myelosuppressive toxicity is limited and reversible, which makes repetitive treatment safe. However, individual studies are difficult to compare, and are hampered by the numerous and different methods used to assess clinical respons. Standardized clinical response assessment using the objective multi-dimensional pain evaluation model should therefore be implemented.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 01:45:33