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Titolo:
VESSELS SUPPLYING SEPTA AND TENDONS AS FUNCTIONAL SHUNTS IN PERFUSED RAT HINDLIMB
Autore:
NEWMAN JMB; STEEN JT; CLARK MG;
Indirizzi:
UNIV TASMANIA,SCH MED,DIV BIOCHEM HOBART TAS 7001 AUSTRALIA
Titolo Testata:
Microvascular research
fascicolo: 1, volume: 54, anno: 1997,
pagine: 49 - 57
SICI:
0026-2862(1997)54:1<49:VSSATA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKELETAL-MUSCLE; HETEROGENEITY; FLOW;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
J.M.B. Newman et al., "VESSELS SUPPLYING SEPTA AND TENDONS AS FUNCTIONAL SHUNTS IN PERFUSED RAT HINDLIMB", Microvascular research, 54(1), 1997, pp. 49-57

Abstract

An assessment was made of the relationship between vasoconstrictor-mediated changes in metabolism and the apparent flow in putative nonnutritive vessels of muscle located on tendon. Surgically isolated rat hindlimbs were perfused at constant flow while monitoring perfusion pressure and venous pO(2). In addition exposed tibial tendon vessels of thebiceps femoris muscle of the perfused leg were positioned either under a surface fluorometer probe to monitor signal strength when pulses of fluorescein isothiocyanate dextran were infused or over the objective lens of an inverted microscope for photography when pulses of India ink were infused. Measurements were conducted under steady state with vehicle, norepinephrine, or serotonin infused. Norepinephrine increased perfusion pressure and oxygen uptake (VO2), but decreased fluorescence signal from the tendon vessels. Photomicroscopy confirmed that the vessels had generally decreased in diameter. Serotonin also increased perfusion pressure but decreased VO2 and increased fluorescence signalfrom the tendon vessels. Photomicroscopy confirmed that serotonin infusion had led to a marked increase in diameter of the vessels. It is concluded that a reciprocal relationship exists between resting muscle metabolism as controlled by vasoconstrictors and flow-through muscle tendon vessels. (C) 1997 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/10/20 alle ore 12:50:56