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Titolo:
Insertion/deletion polymorphism of the serotonin transporter gene and neuroticism as a temperament trait in affective patients and healthy individuals
Autore:
Golimbet, VE; Alfimova, MV; Shcherbatykh, TV; Abramova, LI; Kaleda, VG; Rogaev, EI;
Indirizzi:
Russian Acad Med Sci, Mental Hlth Res Ctr, Moscow 115522, Russia Russian Acad Med Sci Moscow Russia 115522 Res Ctr, Moscow 115522, Russia
Titolo Testata:
MOLECULAR BIOLOGY
fascicolo: 3, volume: 35, anno: 2001,
pagine: 336 - 338
SICI:
0026-8933(200105/06)35:3<336:IPOTST>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANXIETY-RELATED TRAITS; REGULATORY REGION POLYMORPHISM; PERSONALITY; ASSOCIATION; DEPRESSION; JAPANESE; FAMILY;
Keywords:
insertion/deletion polymorphism; serotonin transporter gene; neuroticism; association;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Golimbet, VE Russian Acad Med Sci, Mental Hlth Res Ctr, Moscow 115522, Russia Russian Acad Med Sci Moscow Russia 115522 ow 115522, Russia
Citazione:
V.E. Golimbet et al., "Insertion/deletion polymorphism of the serotonin transporter gene and neuroticism as a temperament trait in affective patients and healthy individuals", MOL BIOL, 35(3), 2001, pp. 336-338

Abstract

Some studies associate the insertion/deletion polymorphism of the serotonin transporter (5-HTT) gene with anxiety related personality traits in mentally healthy people, the short (s) allele being associated with a higher neuroticism score. The 5-HTT genotype and neuroticism score were established fur 114 affective patients, 87 healthy relatives of endogenous psychosis patients, and for 156 mentally healthy people without familial psychiatric history. The effects of sex and age on the association between the two parameters was studied. Neuroticism proved to be not associated with the 5-HTT genotype.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 12:53:37