Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Liver and biliary system pathology in equine dysautonomia - (Grass sickness)
Autore:
Marrs, J; Small, J; Milne, EM; John, HA;
Indirizzi:
Moredun Res Inst, Penicuk HH26 0PZ, Midlothian, Scotland Moredun Res InstPenicuk Midlothian Scotland HH26 0PZ idlothian, Scotland Univ Edinburgh, Royal Dick Sch Vet Studies, Dept Vet Clin Studies, Easter Bush Vet Ctr, Roslin EH25 9RG, Midlothian, Scotland Univ Edinburgh Roslin Midlothian Scotland EH25 9RG , Midlothian, Scotland
Titolo Testata:
JOURNAL OF VETERINARY MEDICINE SERIES A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE
fascicolo: 4, volume: 48, anno: 2001,
pagine: 243 - 255
SICI:
0931-184X(200105)48:4<243:LABSPI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROPATHY; FEATURES; HORSES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: John, HA Moredun Res Inst, Pentlands Sci Pk,Bush Loan, Penicuk HH26 0PZ, Midlothian, Scotland Moredun Res Inst Pentlands Sci Pk,Bush Loan Penicuk Midlothian Scotland HH26 0PZ
Citazione:
J. Marrs et al., "Liver and biliary system pathology in equine dysautonomia - (Grass sickness)", J VET MED A, 48(4), 2001, pp. 243-255

Abstract

Hepatocellular and hepatobiliary damage was assessed in equine acute, subacute nad chronic grass sickness cases (AGS, SAGS, CGS). Histopathological analysis showed that even in some early AGS cases enlarged hepatocytes, hepatocyte vacuolation indicative of lipid accumulation (steatosis), intrahepatocyte, canalicular and periportal deposition of pigments, frequent leucocyte infiltration and cholangitis occurred. Analysis of scrum indicated significantly increased levels of unconjugated bilirubin in all groups and conjugated bilirubin in AGS and SAGS groups, increased levels of bile acids in some individuals from each group and significantly increased levels of glutamate dehydrogenase (GLDII) in AGS and SAGS cases. Conjugated bilirubin was significantly elevated in urine of AGS and SAGS cases. The evidence suggeststhat abnormal liver function involving moderate hepatocellular pathology in conjunction with steatosis and cholestasis may contribute to the pathogenesis of GS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/02/20 alle ore 08:18:51