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Titolo:
Psychological, autonomic and neuroendocrine responses to acute stressors in the combined dexamethasone/CRH test: a study in healthy subjects
Autore:
Oshima, A; Miyano, H; Yamashita, S; Owashi, T; Suzuki, S; Sakano, Y; Higuchi, T;
Indirizzi:
Kohnodai Hosp, Natl Ctr Neurol & Psychiat, Chiba 2728516, Japan Kohnodai Hosp Chiba Japan 2728516 eurol & Psychiat, Chiba 2728516, Japan Showa Univ, Fujigaoka Hosp, Dept Neuropsychiat, Yokohama, Kanagawa 227, Japan Showa Univ Yokohama Kanagawa Japan 227 iat, Yokohama, Kanagawa 227, Japan Emory Univ, Sch Med, Dept Psychiat & Behav Sci, Atlanta, GA USA Emory Univ Atlanta GA USA ed, Dept Psychiat & Behav Sci, Atlanta, GA USA Okayama Prefectural Univ, Fac Hlth & Welf Sci, Okayama, Japan Okayama Prefectural Univ Okayama Japan Hlth & Welf Sci, Okayama, Japan
Titolo Testata:
JOURNAL OF PSYCHIATRIC RESEARCH
fascicolo: 2, volume: 35, anno: 2001,
pagine: 95 - 104
SICI:
0022-3956(200103/04)35:2<95:PAANRT>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE COLD-EXPOSURE; SUPPRESSION TEST; PARAVENTRICULAR NUCLEUS; EXPRESSING NEURONS; DEPRESSED-PATIENTS; LABORATORY TEST; HORMONE TEST; HUMAN-PLASMA; CRH TEST; DISORDERS;
Keywords:
cold pressor; mental arithmetic; hypothalamic-pituitary-adrenal axis; sympathetic nervous system;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Higuchi, T Kohnodai Hosp, Natl Ctr Neurol & Psychiat, 1-7-1 Kohnodai, Chiba 2728516, Japan Kohnodai Hosp 1-7-1 Kohnodai Chiba Japan 2728516 728516, Japan
Citazione:
A. Oshima et al., "Psychological, autonomic and neuroendocrine responses to acute stressors in the combined dexamethasone/CRH test: a study in healthy subjects", J PSYCH RES, 35(2), 2001, pp. 95-104

Abstract

The combined dexamethasone/CRH test (DEX/CRH test) is reported to produce augmented ACTH and cortisol responses in various psychiatric disorders as well as in some non-psychiatric conditions. To examine whether stress affects the outcome of DEX/CRH test, two stress groups in a repeated measures design were compared to an age-matched control group with regard to the psychological. autonomic and neuroendocrine responses after the combined dexamethasone and CRH challenge. Cold presser (4 degreesC, total 10 min) produced stronger subjective distress than mental arithmetic (15 min). Cold exposure,but not the mental test, elevated systolic and diastolic blood pressure, whereas the mental test increased pulse rate and skin conductance level moremarkedly than cold exposure. Neither stressor produced a significantly enhanced response of ACTH and cortisol in DEX/CRH test, and there was no correlation between psychological and neuroendocrine responses. These findings suggest that different stressors induce different patterns of sympathetic activation and that acute stress is unlikely to affect the results of DEX/CRHtest. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 07:23:49