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Titolo:
Citalopram in refractory obsessive-compulsive disorder: an open study
Autore:
Marazziti, D; DellOsso, L; Gemignani, A; Ciapparelli, A; Presta, S; Di Nasso, E; Pfanner, C; Cassano, GB;
Indirizzi:
Univ Pisa, Dipartimento Psichiatria Neurobiol Farmacol & Bio, I-56100 Pisa, Italy Univ Pisa Pisa Italy I-56100 urobiol Farmacol & Bio, I-56100 Pisa, Italy
Titolo Testata:
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
fascicolo: 4, volume: 16, anno: 2001,
pagine: 215 - 219
SICI:
0268-1315(200107)16:4<215:CIRODA>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOUBLE-BLIND; EFFICACY; FLUVOXAMINE; SEROTONIN; PLACEBO;
Keywords:
augmentation strategics; citalopram; obsessive-compulsive disorder; serotonin reuptake inhibitors;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Marazziti, D Univ Pisa, Dipartimento Psichiatria Neurobiol Farmacol & Bio,Via Roma 67,I-56100 Pisa, Italy Univ Pisa Via Roma 67 Pisa Italy I-56100 I-56100 Pisa, Italy
Citazione:
D. Marazziti et al., "Citalopram in refractory obsessive-compulsive disorder: an open study", INT CLIN PS, 16(4), 2001, pp. 215-219

Abstract

This study aimed to evaluate the effect of citalopram in patients with refractory obsessive-compulsive disorder (OCD) which had not responded to previous antiobsessional treatments. Eighteen patients were selected for this study: they had been suffering from OCD, according to DSM-IV criteria, for at least 2 years and had various comorbid disorders. All had been treated with serotonin reuptake inhibitors at adequate dosages for at least 6 months,but had failed to respond. Consequently, they were shifted to citalopram, titrated up to the dose of 40 mg, within 2 weeks. After 4 months of this regimen, 14 out of the total of 18 patients had shown a reduction in OC symptoms, as assessed by the decrease in the Yale-Brown Obsessive Compulsive Scale total score; no relevant side-effects were reported, except for a mild nausea in four patients within the first few days of treatment, which quickly disappeared. The use of citalopram would appear to be an useful strategy in refractory OCD cases. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 11:07:30