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Titolo:
Atypical primary sclerosing cholangitis cases associated with unusual pancreatitis
Autore:
Nakazawa, T; Ohara, H; Yamada, T; Ando, H; Sano, H; Kajino, S; Hashimoto, T; Nakamura, S; Ando, T; Nomura, T; Joh, T; Itoh, M;
Indirizzi:
Nagoya City Univ, Sch Med, Dept Internal Med 1, Mizuho Ku, Nagoya, Aichi 4678601, Japan Nagoya City Univ Nagoya Aichi Japan 4678601 Nagoya, Aichi 4678601, Japan
Titolo Testata:
HEPATO-GASTROENTEROLOGY
fascicolo: 39, volume: 48, anno: 2001,
pagine: 625 - 630
SICI:
0172-6390(200105/06)48:39<625:APSCCA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARBONIC-ANHYDRASE; SJOGRENS-SYNDROME;
Keywords:
PSC; primary sclerosing cholangitis; chronic pancreatitis; autoimmune pancreatitis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Nakazawa, T Nagoya City Univ, Sch Med, Dept Internal Med 1, Mizuho Ku, 1 Kawasumi, Nagoya, Aichi 4678601, Japan Nagoya City Univ 1 Kawasumi Nagoya Aichi Japan 4678601 , Japan
Citazione:
T. Nakazawa et al., "Atypical primary sclerosing cholangitis cases associated with unusual pancreatitis", HEP-GASTRO, 48(39), 2001, pp. 625-630

Abstract

Background/Aims: We encountered one group of primary sclerosing cholangitis cases which met classic criteria, but demonstrated better clinical courses. Methodology: We evaluated the clinical characteristics of several cases ofprimary sclerosing cholangitis, especially those associated with chronic pancreatitis. Results: Of a total of 25 cases, eight had a background of pancreatitis with unusual irregularly segmental or diffuse narrowing features on pancreatography. Abdominal ultrasonography and computed tomography also revealed segmental or diffuse enlargement of the pancreas. Pathological findings of surgical specimens in two cases pointed to lymphoplasmacytic sclerosing pancreatitis. The walls of the lower biliary ducts were also thickened with a similar appearance to the pancreatic ducts. In seven cases, cholangiography displayed stenosis of the lower part of the common bile duct and in one case,only the hepatic hilar region was affected. In this case both biliary and pancreatic lesions responded to steroid therapy simultaneously. One case developed hepatic hilar stenosis four months after a lesion in the lower partof the common bile duct had disappeared. The cases of primary sclerosing cholangitis with pancreatitis demonstrated better clinical courses than did typical cases of primary sclerosing cholangitis. Six cases were characterized by autoimmunological abnormalities. Conclusions: We concluded that similar etiological agents might impact on both the pancreas and biliary tract, either simultaneously or in sequence. We propose new criteria for these atypical primary sclerosing cholangitis cases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/07/20 alle ore 05:55:15