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Titolo:
Electrochemical potentials during radiofrequency energy delivery: a new method to control catheter ablation of arrhythmias
Autore:
Erdogan, A; Carlsson, J; Grumbrecht, S; Kostin, S; Schulte, B; Schlapp, M; Neuzner, J; Pitschner, HF;
Indirizzi:
Kerckhoff Heart Ctr, Dept Cardiol, D-61231 Bad Nauheim, Germany Kerckhoff Heart Ctr Bad Nauheim Germany D-61231 231 Bad Nauheim, Germany Max Planck Inst Expt Cardiol, D-61231 Bad Nauheim, Germany Max Planck InstExpt Cardiol Bad Nauheim Germany D-61231 auheim, Germany
Titolo Testata:
EUROPACE
fascicolo: 3, volume: 3, anno: 2001,
pagine: 201 - 207
SICI:
1099-5129(200107)3:3<201:EPDRED>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
ATRIOVENTRICULAR JUNCTION; TEMPERATURE RESPONSE; CARDIAC-ARRHYTHMIAS; LESION; MYOCARDIUM; ELECTRODE;
Keywords:
radiofrequency catheter ablation; potential measurement; energy control;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Erdogan, A Univ Giessen, Dept Cardiol, Klinikstr 36, D-35392 Giessen, Germany Univ Giessen Klinikstr 36 Giessen Germany D-35392 sen, Germany
Citazione:
A. Erdogan et al., "Electrochemical potentials during radiofrequency energy delivery: a new method to control catheter ablation of arrhythmias", EUROPACE, 3(3), 2001, pp. 201-207

Abstract

Aims Thermal injury of subendocardial tissue leads to a release of electrolytes and free radicals from the intracellular site creating a change in electrochemical potential (eP) between the distal and the proximal catheter tip electrodes. The aim of the study was to verify the detection of ablation-induced release of electrolytes and free radicals and to assess the suitability of control-line energy delivery at ablation by measuring eP. Methods and Results In vitro tests under constant flow conditions were performed in a 101 bath of physiological saline solution or bovine blood. Endomyocardial preparations of fresh bovine hearts were used. Closed-loop temperature-controlled, irrigated and closed-loop eP-controlled ablations were performed. In vivo animal investigations were performed in six anaesthetizedand ventilated Digs. The existence of the eP was established in the tank model and was confirmed in animal investigations. High correlations were found between eP and catheter tip temperature (r=087) and between maximum eP and induced lesion size (r=0(.)85). Also a high correlation (r=0(.)85, P <0(.)001) was found between eP and lesion volume. Conclusions Control of energy delivery during RF ablation by the measurement of eP is feasible. In comparison with temperature controlled RF ablation, ablation guided by eP-measurement revealed a superior correlation with induced lesion size. Especially during cooled radiofrequency catheter ablation eP is the only parameter for control of energy delivery. (C) 2001 The European Society of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 06:57:15