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Titolo:
Static lung compliance as an index of early pulmonary disease in systemic sclerosis
Autore:
Sud, A; Gupta, D; Wanchu, A; Jindal, SK; Bambery, P;
Indirizzi:
Postgrad Inst Med Educ & Res, Dept Internal Med, Rheumatol Serv, Chandigarh 160012, India Postgrad Inst Med Educ & Res Chandigarh India 160012 igarh 160012, India
Titolo Testata:
CLINICAL RHEUMATOLOGY
fascicolo: 3, volume: 20, anno: 2001,
pagine: 177 - 180
SICI:
0770-3198(2001)20:3<177:SLCAAI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIFFUSING-CAPACITY; SCLERODERMA; THERAPY;
Keywords:
progressive systemic sclerosis; pulmonary fibrosis; scleroderma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Sud, A Postgrad Inst Med Educ & Res, Dept Internal Med, Rheumatol Serv, Chandigarh 160012, India Postgrad Inst Med Educ & Res Chandigarh India 160012 60012, India
Citazione:
A. Sud et al., "Static lung compliance as an index of early pulmonary disease in systemic sclerosis", CLIN RHEUMA, 20(3), 2001, pp. 177-180

Abstract

Pulmonary function abnormalities constitute the most important cause of morbidity and mortality in patients with systemic sclerosis (SSc). A restrictive ventilatory defect with a reduction in pulmonary carbon monoxide diffusion capacity (DLCO) is the commonest finding. Static lung compliance (Cst) is perhaps the most sensitive parameter for the detection of abnormal pulmonary mechanics. We compared the results of Cst and DLCO in patients with SSc and normal spirometry to identify early pulmonary disease. Sixteen of 50 patients had normal spirometry, eight of whom had abnormal Cst. Four of them also had a reduced DLCO. Two patients had abnormal DLCO but their Cst wasnormal. One of them had pulmonary hypertension on echocardiography. We conclude that Cst was helpful in diagnosing early pulmonary abnormality in 50%of patients with normal spirometry. Among these patients Cst was a better index of abnormality than DLCO.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 11:31:28