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Titolo:
Milk basic protein promotes bone formation and suppresses bone resorption in healthy adult men
Autore:
Toba, Y; Takada, Y; Matsuoka, Y; Morita, Y; Motouri, M; Hirai, T; Suguri, T; Aoe, S; Kawakami, H; Kumegawa, M; Takeuchi, A; Itabashi, A;
Indirizzi:
Snow Brand Milk Prod Co Ltd, Technol & Res Inst, Kawagoe, Saitama 3501165,Japan Snow Brand Milk Prod Co Ltd Kawagoe Saitama Japan 3501165 a 3501165,Japan Snow Brand Milk Prod Co Ltd, Prod Planning Dept, Kawagoe, Saitama 3501165,Japan Snow Brand Milk Prod Co Ltd Kawagoe Saitama Japan 3501165 a 3501165,Japan Meikai Univ Dent, Dept Oral Anat, Kakado, Saitama 3500248, Japan Meikai Univ Dent Kakado Saitama Japan 3500248 ado, Saitama 3500248, Japan Luke Hosp, Tokyo 1650027, Japan Luke Hosp Tokyo Japan 1650027Luke Hosp, Tokyo 1650027, Japan Saitama Med Sch, Cent Clin Lab, Kawagoe, Saitama 3500495, Japan Saitama Med Sch Kawagoe Saitama Japan 3500495 goe, Saitama 3500495, Japan
Titolo Testata:
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
fascicolo: 6, volume: 65, anno: 2001,
pagine: 1353 - 1357
SICI:
0916-8451(200106)65:6<1353:MBPPBF>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
OSTEOBLASTIC MC3T3-E1 CELLS; WHEY-PROTEIN; OVARIECTOMIZED RATS; CYSTATIN-C; CALCIUM; PROLIFERATION; BIOAVAILABILITY; OSTEOPOROSIS; INHIBITOR;
Keywords:
milk basic protein; bone formation; bone resorption; remodeling; healthy adult men;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Toba, Y Snow Brand Milk Prod Co Ltd, Technol & Res Inst, 1-1-2 Minamidai, Kawagoe,Saitama 3501165, Japan Snow Brand Milk Prod Co Ltd 1-1-2 Minamidai Kawagoe Saitama Japan 3501165
Citazione:
Y. Toba et al., "Milk basic protein promotes bone formation and suppresses bone resorption in healthy adult men", BIOS BIOT B, 65(6), 2001, pp. 1353-1357

Abstract

Milk contains several components effective for bone health. In the previous in vitro and in vivo studies, we have shown that milk whey protein, especially its basic protein fraction (milk basic protein [MBP]), promoted bone formation and suppressed bone resorption. This present study examines the effect of MBP on the biochemical markers of bone metabolism in healthy adultmen. Experimental beverages containing MBP (300 mg of MBP a day) were given to 30 normal healthy adult men for 16 days. The serum osteocalcin concentration had increased significantly after 16 days of ingesting the experimental beverage containing MBP. Urinary cross-linked N-teleopeptides of type-Icollagen (NTx) excretion had decreased significantly after 16 days of ingesting MBP. The urinary NTx excretion was related to the serum osteocalcin concentration after 16 days of ingestion. These results suggest that MBP promoted bone formation and suppressed bone resorption, while maintaining the balance of bone remodeling.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 09:00:28