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Titolo:
Epidemiology of endometrial cancer
Autore:
Purdie, DM; Green, AC;
Indirizzi:
Royal Brisbane Hosp, Queensland Inst Med Res, Populat & Clin Sci Div, Brisbane, Qld 4029, Australia Royal Brisbane Hosp Brisbane Qld Australia 4029 bane, Qld 4029, Australia
Titolo Testata:
BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY
fascicolo: 3, volume: 15, anno: 2001,
pagine: 341 - 354
SICI:
1521-6934(200106)15:3<341:EOEC>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
BODY-FAT DISTRIBUTION; ITALIAN CASE-CONTROL; ESTROGEN REPLACEMENT THERAPY; POST-MENOPAUSAL WOMEN; CIGARETTE-SMOKING; POSTMENOPAUSAL WOMEN; RISK-FACTORS; HORMONE CONCENTRATIONS; CONJUGATED ESTROGENS; ORAL-CONTRACEPTIVES;
Keywords:
endometrial cancer; epidemiology; incidence; risk factors;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
100
Recensione:
Indirizzi per estratti:
Indirizzo: Purdie, DM Royal Brisbane Hosp, Queensland Inst Med Res, Populat & Clin Sci Div, Brisbane, Qld 4029, Australia Royal Brisbane Hosp Brisbane Qld Australia 4029 029, Australia
Citazione:
D.M. Purdie e A.C. Green, "Epidemiology of endometrial cancer", BEST P R CL, 15(3), 2001, pp. 341-354

Abstract

Endometrial cancer is the commonest gynaecological cancer mostly affectingwomen in the post-menopausal age group. Rates vary worldwide and are highest in white women in Western populations. Some risk factors are related to reproduction, such as early age at menarche, late age at menopause and nulliparity, while others are more directly oestrogen-related, for example, conditions such as the polycystic ovarian syndrome. Use of unopposed oestrogenreplacement therapy is associated with an increased risk, and use of the combined oral contraceptive pill is associated with a decreased risk. The relationship between tamoxifen and endometrial cancer is not established. Obesity, diabetes and hypertension increase the risk of endometrial cancer while smoking, low-fat diets and physical exercise appear to decrease the risk; all of these possibly exert their effects by various indirect influences on oestrogen levels, thus influencing the level of stimulation of the target endometrial epithelium.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:08:27