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Titolo:
CD20-positive T cell leukemia/lymphoma: case report and review of the literature
Autore:
Yokose, N; Ogata, K; Sugisaki, Y; Mori, S; Yamada, T; An, E; Dan, K;
Indirizzi:
Nippon Med Sch, Dept Internal Med 3, Bunkyo Ku, Tokyo 1138603, Japan Nippon Med Sch Tokyo Japan 1138603 ed 3, Bunkyo Ku, Tokyo 1138603, Japan Nippon Med Sch, Dept Surg Pathol, Bunkyo Ku, Tokyo 1138603, Japan Nippon Med Sch Tokyo Japan 1138603 thol, Bunkyo Ku, Tokyo 1138603, Japan Univ Tokyo, Inst Med Sci, Dept Pathol, Minato Ku, Tokyo 1088639, Japan Univ Tokyo Tokyo Japan 1088639 t Pathol, Minato Ku, Tokyo 1088639, Japan
Titolo Testata:
ANNALS OF HEMATOLOGY
fascicolo: 6, volume: 80, anno: 2001,
pagine: 372 - 375
SICI:
0939-5555(200106)80:6<372:CTCLCR>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
NON-HODGKINS LYMPHOMA; LOW-LEVEL; ANTIGEN; EXPRESSION;
Keywords:
CD20 antigens; T cell lymphoma; T cell leukemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Ogata, K Nippon Med Sch, Dept Internal Med 3, Bunkyo Ku, 1-1-5 Sendagi, Tokyo 1138603, Japan Nippon Med Sch 1-1-5 Sendagi Tokyo Japan 1138603 1138603, Japan
Citazione:
N. Yokose et al., "CD20-positive T cell leukemia/lymphoma: case report and review of the literature", ANN HEMATOL, 80(6), 2001, pp. 372-375

Abstract

We report on a case of CD20-positive peripheral T cell lymphoma. The lymphoma cell was positive for CD20 and T cell lineage markers such as cytoplasmic CD3, CD4, and CD5 and had a monoclonal rearrangement of the T cell receptor (TCR) gamma chain gene. The clinical characteristics resembled angioimmunoblastic lymphadenopathy: spontaneous regression of lymphadenopathy and immunological abnormalities such as polyclonal hypergammaglobulinemia, positive results of direct and indirect antiglobulin tests, and a high antinuclear antibody titer, We reviewed seven cases of CD20-positive T cell malignancies including the present case. Three were immature T cell malignancies (acute lymphoblastic leukemia) and four were peripheral T cell malignancies (non-Hodgkin's lymphoma and chronic lymphocytic leukemia). Hepatomegaly and/or splenomegaly were common features, Further cases must be evaluated to understand the clinical significance of the CD20 expression on the surface ofT cell malignancies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 18:42:15