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Titolo:
Conservative treatment of acute deep vein thrombosis of the lower extremity
Autore:
Klein-Weigel, P; Fraedrich, G;
Indirizzi:
Innsbruck Univ, Klin Chirurg, Klin Abt Gafasschirurg, A-6020 Innsbruck, Austria Innsbruck Univ Innsbruck Austria A-6020 irurg, A-6020 Innsbruck, Austria
Titolo Testata:
ZENTRALBLATT FUR CHIRURGIE
fascicolo: 6, volume: 126, anno: 2001,
pagine: 441 - 444
SICI:
0044-409X(200106)126:6<441:CTOADV>2.0.ZU;2-1
Fonte:
ISI
Lingua:
GER
Soggetto:
MOLECULAR-WEIGHT HEPARINS; ORAL ANTICOAGULANT-THERAPY; VENOUS THROMBOSIS; UNFRACTIONATED HEPARIN; INITIAL TREATMENT; FIRST EPISODE; THROMBOEMBOLISM; METAANALYSIS; MANAGEMENT; NOMOGRAM;
Keywords:
deep vein thrombosis; medical treatment; anticoagulation; low-molecular weight heparin; coumarin; compression therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Klein-Weigel, P Innsbruck Univ, Klin Chirurg, Klin Abt Gafasschirurg, Anichstr 35, A-6020 Innsbruck, Austria Innsbruck Univ Anichstr 35 Innsbruck Austria A-6020 stria
Citazione:
P. Klein-Weigel e G. Fraedrich, "Conservative treatment of acute deep vein thrombosis of the lower extremity", ZBL CHIR, 126(6), 2001, pp. 441-444

Abstract

During the acute phase of the disease the aim of conservative treatment ofDVT is relief of symptoms as well as prevention of thrombus progression and pulmonary embolism. In the chronic phase treatment should prevent recurrence and postthrombotic syndrome. Besides general measures such as compression therapy, elevation of the leg and mobilisation anticoagulation therapy with heparin and coumarin has been proved to be successful. Even though not more effective or safer low-molecular weight heparin has recently replaced unfractionated heparin in the initial treatment of DVT mainly because of its more convenient use allowing modem ambulatory and outdoor treatment. Doses depend on the kind of heparin used. In the secondary prevention therapy with coumarins, an WR of 2-3 is generally accepted whereas the duration of oral anticoagulant therapy is under discussion. Compression therapy is recommended for at least 2 years, in case of postthrombotic syndrome life-long therapy is necessary. When comparing the effectivness of DVT-treatment todaywith the results in the preanticoagulant era, the modern treatment is moreeffective, safe and cost-effective; it also guarantees more quality of life, but the long-term results have to be improved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 15:33:19