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Titolo:
Factor VIIa-induced gene expression: Potential implications in pathophysiology
Autore:
Rao, LVM; Pendurthi, UR;
Indirizzi:
Univ Texas Hlth Ctr, Dept Biochem, Biomed Res Div, Tyler, TX 75708 USA Univ Texas Hlth Ctr Tyler TX USA 75708 iomed Res Div, Tyler, TX 75708 USA
Titolo Testata:
TRENDS IN CARDIOVASCULAR MEDICINE
fascicolo: 1, volume: 11, anno: 2001,
pagine: 14 - 21
SICI:
1050-1738(200101)11:1<14:FVGEPI>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
TISSUE GROWTH-FACTOR; IMMEDIATE-EARLY GENE; INDUCED SIGNAL-TRANSDUCTION; COAGULATION-FACTOR VIIA; CANINE KIDNEY-CELLS; COLI SEPTIC SHOCK; ESCHERICHIA-COLI; ENDOTHELIAL-CELLS; HUMAN FIBROBLASTS; BLOOD-COAGULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Rao, LVM Univ Texas Hlth Ctr, Dept Biochem, Biomed Res Div, 11937 US Highway 271, Tyler, TX 75708 USA Univ Texas Hlth Ctr 11937 US Highway 271 Tyler TX USA 75708 8 USA
Citazione:
L.V.M. Rao e U.R. Pendurthi, "Factor VIIa-induced gene expression: Potential implications in pathophysiology", TREND CARD, 11(1), 2001, pp. 14-21

Abstract

Bind of factor VIIa (VIIa) to tissue factor (TF) triggers the coagulation cascade. Several studies indicate a possible role for TF-VIIa in other cellular functions, in addition to coagulation, under pathophysiological conditions. Recent studies suggest that TF-VIIa mediates cell signaling by two distinct mechanisms. TF cytoplasmic domain-dependent and TF-VIIa protease activity-dependent. In this review, we focus upon TF-VIIa protease-induced gene expression and how the altered gene expression could potentially affect various cellular processes. (C) 2001, Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 02:03:22