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Titolo:
Vertebral bone marrow perfusion evaluated with dynamic contrast-enhanced MR imaging: Significance of aging and sex
Autore:
Chen, WT; Shih, TTF; Chen, RC; Lo, SY; Chou, CT; Lee, JM; Tu, HY;
Indirizzi:
Natl Taiwan Univ, Med Coll & Hosp, Dept Radiol, Taipei 100, Taiwan Natl Taiwan Univ Taipei Taiwan 100 Hosp, Dept Radiol, Taipei 100, Taiwan Taipei Municipal Chun Shau Hosp, Dept Radiol, Taipei, Taiwan Taipei Municipal Chun Shau Hosp Taipei Taiwan pt Radiol, Taipei, Taiwan Taipei Municipal Jen Ai Hosp, Dept Radiol, Taipei, Taiwan Taipei MunicipalJen Ai Hosp Taipei Taiwan Dept Radiol, Taipei, Taiwan
Titolo Testata:
RADIOLOGY
fascicolo: 1, volume: 220, anno: 2001,
pagine: 213 - 218
SICI:
0033-8419(200107)220:1<213:VBMPEW>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
MINERAL DENSITY; CHEMOTHERAPY; FRACTURES; CHINESE; AGE;
Keywords:
aging; bone marrow; bone marrow, MR; magnetic resonance (MR), contrast enhancement; magnetic resonance (MR), perfusion study; osteoporosis; spine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Shih, TTF Natl Taiwan Univ, Med Coll & Hosp, Dept Radiol, 7 Chung Shan S Rd, Taipei 100, Taiwan Natl Taiwan Univ 7 Chung Shan S Rd Taipei Taiwan 10000, Taiwan
Citazione:
W.T. Chen et al., "Vertebral bone marrow perfusion evaluated with dynamic contrast-enhanced MR imaging: Significance of aging and sex", RADIOLOGY, 220(1), 2001, pp. 213-218

Abstract

PURPOSE: To investigate blood perfusion of non-fractured, normal-appearingvertebral bodies with regard to age and sex. MATERIALS AND METHODS: Dynamic magnetic resonance imaging (160 images obtained in 80 seconds) was performed from T10 to L5 in 66 patients. Patients were assigned to three groups: group 1, those 50 years or younger without compression fracture; group 2, those older than 50 years without compression fracture; or group 3, those older than 50 years with compression fracture. Peak enhancement percentage and enhancement slope were determined from the time-intensity curve of normal (nonfractured) vertebral body. Comparisons were made between groups, and the effect of age and sex interaction was analyzed. RESULTS: Higher peak enhancement percentage was demonstrated for group 1 compared with group 2 (58.21 +/- 44.65 [SD] vs 21.88 +/- 14.77, P < .005). Group; 1 women revealed a higher enhancement percentage compared with group 1 men (87.17 +/- 54.13 vs 38.16 +/- 21.69, P > .05), which significantly decreased in those older than 50 years (from 87.17 +/- 54.13 to 17.98 +/- 13.80, P < .005). For men, this decrease in those older than 50 years was not as pronounced (from 38.16 +/- 21.69 to 25.38 +/- 15.43, P > .05). Presence of compression fracture at other levels of the spine (group 3) was not associated with a different enhancement percentage for normal vertebrae. CONCLUSION: Rate of vertebral bone marrow perfusion revealed a significantdecrease in subjects older than 50 years; Women demonstrated a higher marrow perfusion rate than men younger than 50 years and a more marked decreasethan men older than 50 years.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 04:11:44