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Titolo:
Studies on the antidiarrhoeal effect of dragon's blood from Croton urucurana
Autore:
Gurgel, LA; Silva, RM; Santos, FA; Martins, DTO; Mattos, PO; Rao, VSN;
Indirizzi:
Univ Fed Ceara, FM, Dept Fisiol & Farmacol, BR-60430270 Fortaleza, Ceara, Brazil Univ Fed Ceara Fortaleza Ceara Brazil BR-60430270 BCtaleza, Ceara, Brazil Univ Fed Mato Grosso, FCM, Dept Ciencias Bas Saude, BR-78060900 Cuiaba, MT, Brazil Univ Fed Mato Grosso Cuiaba MT Brazil BR-78060900 BC00 Cuiaba, MT, Brazil
Titolo Testata:
PHYTOTHERAPY RESEARCH
fascicolo: 4, volume: 15, anno: 2001,
pagine: 319 - 322
SICI:
0951-418X(200106)15:4<319:SOTAEO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYSTIC-FIBROSIS; SOUTH-AMERICA; NITRIC-OXIDE; MOUSE MODEL; LECHLERI; BAILLON; TOXIN;
Keywords:
Croton urucurana Baill.; Euphorbiaceae; dragon's blood; antidiarrhoeal activity; castor oil-induced diarrhoea; cholera toxin-induced intestinal secretion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Rao, VSN Univ Fed Ceara, FM, Dept Fisiol & Farmacol, CP 3157, BR-60430270 Fortaleza, Ceara, Brazil Univ Fed Ceara CP 3157 Fortaleza Ceara Brazil BR-60430270 BCrazil
Citazione:
L.A. Gurgel et al., "Studies on the antidiarrhoeal effect of dragon's blood from Croton urucurana", PHYTOTHER R, 15(4), 2001, pp. 319-322

Abstract

The red sap obtained by slashing the bark of Croton urucurana Baill. (Euphorbiaceae), also known as dragon's blood, was screened for a possible antidiarrhoeal activity on castor oil-induced diarrhoea in rats, cholera toxin-induced intestinal secretion in mice and on small intestinal transit in mice. Dragon's blood at an oral dose of 600 mg/kg caused in marked inhibition of the diarrhoeal response following castor oil administration as well as the intestinal fluid accumulation promoted by cholera toxin, At a similar dose the red sap significantly inhibited the small intestinal transit which was, however, found to be independent of the opioid mechanism. These results suggest a potential usefulness of the red sap from Croton urucurana Baill, in the control of secretory diarrhoea associated pathologies, Copyright (C)2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 12:45:22