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Titolo:
Elevation of prefrontal acetylcholine is related to the extinction of learned behavior in rats
Autore:
Izaki, Y; Hori, K; Nomura, M;
Indirizzi:
Saitama Med Sch, Dept Physiol, Moroyama, Saitama 3500495, Japan Saitama Med Sch Moroyama Saitama Japan 3500495 ma, Saitama 3500495, Japan Rikkyo Univ, Dept Psychol, Tokyo 1718501, Japan Rikkyo Univ Tokyo Japan 1718501 Univ, Dept Psychol, Tokyo 1718501, Japan
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 1-2, volume: 306, anno: 2001,
pagine: 33 - 36
SICI:
0304-3940(20010622)306:1-2<33:EOPAIR>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTEX; RELEASE; MICRODIALYSIS; INVOLVEMENT; DOPAMINE; MEMORY;
Keywords:
medial prefrontal cortex; acetylcholine; in vivo microdialysis; lever-press; extinction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Izaki, Y Saitama Med Sch, Dept Physiol, Moroyama, Saitama 3500495, Japan Saitama Med Sch Moroyama Saitama Japan 3500495 ma 3500495, Japan
Citazione:
Y. Izaki et al., "Elevation of prefrontal acetylcholine is related to the extinction of learned behavior in rats", NEUROSCI L, 306(1-2), 2001, pp. 33-36

Abstract

To investigate whether changes occur in acetylcholine (ACh) levels in the rat medial prefrontal cortex (mPFC) during initial lever-press extinction training, in vivo microdialysis was used to measure mPFC ACh. Elevated ACh was found during this training period. Furthermore, this elevation significantly correlated with the number of responses found in the re-training session the next day, but not with that in the initial training. These results suggest that the mPFC ACh elevation during the initial training period enhances the progress of lever-press extinction across sessions. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 08:28:36