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Titolo:
Perfusion imaging using spin-labeling methods: Contrast-to-noise comparison in functional MRI applications
Autore:
Preibisch, C; Haase, A;
Indirizzi:
Univ Wurzburg, Inst Phys, Lehrstuhl Expt Phys 5, D-97074 Wurzburg, GermanyUniv Wurzburg Wurzburg Germany D-97074 Phys 5, D-97074 Wurzburg, Germany Univ Frankfurt Klinikum, ZRAD, Inst Neuroradiol, D-6000 Frankfurt, GermanyUniv Frankfurt Klinikum Frankfurt Germany D-6000 6000 Frankfurt, Germany
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 1, volume: 46, anno: 2001,
pagine: 172 - 182
SICI:
0740-3194(200107)46:1<172:PIUSMC>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; RECOVERY FAIR TECHNIQUE; SENSORY STIMULATION; BRAIN ACTIVATION; ARTERIAL WATER; RAT-BRAIN; OXYGENATION; FLASH; INVERSION; MODEL;
Keywords:
fMRI; perfusion; spin-labeling; CNR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Haase, A Univ Wurzburg, Inst Phys, Lehrstuhl Expt Phys 5, Hubland, D-97074Wurzburg, Germany Univ Wurzburg Hubland Wurzburg Germany D-97074 Wurzburg, Germany
Citazione:
C. Preibisch e A. Haase, "Perfusion imaging using spin-labeling methods: Contrast-to-noise comparison in functional MRI applications", MAGN RES M, 46(1), 2001, pp. 172-182

Abstract

In this study the performance of FLASH imaging with selective inversion preparation for functional perfusion studies was investigated, In addition tothe absolute quantification of perfusion by measurement of the longitudinal relaxation times with global (T-1glob) and selective (T-1set) inversion, the measurement of absolute (BASE) and relative (FAIR) perfusion increases by subtraction of appropriately weighted images was also considered, The subject averages of absolute perfusion obtained by the quantitative method were 70.7 +/- 4.0 ml/100g/min in gray matter, 10.2 +/- 3.4 ml/100g/min in white matter, and 89.0 +/- 3.1 ml/100g/min in visual cortex. These values, as well as the average increase of perfusion due to visual stimulation (44.4 +/- 3.7 ml/100g/min), agree well with respective data reported by PET and other MRI studies, However, for individual subjects the standard deviations over single ROls inside the visual cortex lay around 100% which prevented the detection of significant activation, BASE and FAIR, on the other hand, were able to detect significant activation in single subjects. The measured average perfusion increases were 51.7 +/- 6.6 ml/100g/min and 56.5 +/- 13.8%, respectively, Magn Reson Med 46:172-182, 2001, (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 06:31:00