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Titolo:
Theoretical analysis of the effect of imperfect slice profiles on tagging schemes for pulsed arterial spin labeling MRI
Autore:
Keilholz-George, SD; Knight-Scott, J; Berr, SS;
Indirizzi:
Univ Virginia, Hlth Sci Ctr, Sch Engn, Engn Phys Program, Charlottesville,VA 22908 USA Univ Virginia Charlottesville VA USA 22908 , Charlottesville,VA 22908 USA Univ Virginia, Hlth Sci Ctr, Dept Radiol, Charlottesville, VA 22908 USA Univ Virginia Charlottesville VA USA 22908 Charlottesville, VA 22908 USA Univ Virginia, Dept Biomed Engn, Charlottesville, VA 22908 USA Univ Virginia Charlottesville VA USA 22908 Charlottesville, VA 22908 USA
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 1, volume: 46, anno: 2001,
pagine: 141 - 148
SICI:
0740-3194(200107)46:1<141:TAOTEO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALTERNATING INVERSION-RECOVERY; CEREBRAL BLOOD-FLOW; MAGNETIC-RESONANCE; FAIR TECHNIQUE; QUIPSS-II; PERFUSION; QUANTIFICATION; FREQUENCY; MODEL; WATER;
Keywords:
arterial spin labeling; perfusion; imperfect slice profiles;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Berr, SS Univ Virginia, Hlth Sci Ctr, Sch Engn, Engn Phys Program, POB 801332,MR4 Bldg,Room 1192, Charlottesville, VA 22908 USA Univ Virginia POB 801332,MR4 Bldg,Room 1192 Charlottesville VA USA 22908
Citazione:
S.D. Keilholz-George et al., "Theoretical analysis of the effect of imperfect slice profiles on tagging schemes for pulsed arterial spin labeling MRI", MAGN RES M, 46(1), 2001, pp. 141-148

Abstract

Pulsed arterial spin labeling (ASL) techniques provide a noninvasive method of obtaining qualitative and quantitative perfusion images with MRI, ASL techniques employ inversion recovery and/or saturation recovery to induce perfusion weighting, and thus the performance of these techniques is dependent on the slice profiles of the inversion or saturation pulses. This article systematically examines through simulations the effects of slice profile imperfections on the perfusion signal for nine labeling schemes, including FAIR, FAIRER, and EST (UNFAIR), Each sequence is evaluated for quantitativeaccuracy, suppression of stationary signal, and magnitude of perfusion signal. Perfusion effects are modeled from a modified Bloch equation and experimentally determined slice profiles. The results show that FAIR, FAIRER, and EST have excellent tissue suppression. The magnitude of the perfusion signal is comparable for FAIR and FAIRER, with EST providing a slightly weakersignal. For quantitative measurements, all three methods underestimate theperfusion signal by more than 20%, Of the additional six ASL techniques examined, only one performed well in this model. This method, which combines inversion and saturation recovery, yields improved signal accuracy(< 15% difference from the theoretical value) and tissue suppression similar to thatof FAIR and its variants, but has only half the signal. Magn Reson Med 46:141-148, 2001, (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:58:20