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Titolo:
Background suppression using magnetization preparation for contrast-enhanced MR projection angiography
Autore:
Bos, C; Bakker, CJG; Viergever, MA;
Indirizzi:
Univ Utrecht, Med Ctr, Dept Radiol, Image Sci Inst, NL-3508 TC Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3508 TC 3508 TC Utrecht, Netherlands
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 1, volume: 46, anno: 2001,
pagine: 78 - 87
SICI:
0740-3194(200107)46:1<78:BSUMPF>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIGITAL SUBTRACTION ANGIOGRAPHY; SELECTIVE INVERSION-RECOVERY; COMPLEX SUBTRACTION; RENAL-ARTERIES; VISUALIZATION; ACQUISITION; INTERVENTIONS; SATURATION; SEQUENCES; TRACKING;
Keywords:
contrast-enhanced MRA; projection angiography; background suppression; slice profile; magnetization preparation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Bos, C AZU, Room E01-334,Heidelberglaan 100, NL-3584 CX Utrecht, Netherlands AZU Room E01-334,Heidelberglaan 100 Utrecht Netherlands NL-3584 CX
Citazione:
C. Bos et al., "Background suppression using magnetization preparation for contrast-enhanced MR projection angiography", MAGN RES M, 46(1), 2001, pp. 78-87

Abstract

In contrast-enhanced MR projection angiography, vessel conspicuity is determined by the T-1-weighted signal difference between blood and surrounding tissues. For slice-selective excitation pulses, the excitation angle Variesacross the slice, leading to: poor saturation of the background signal at the slice edge and reducing the blood-background signal difference. This work reports on the use of magnetization preparation to enhance the T-1-weighted contrast between blood and background tissue. Applying the prepulse nonselectively reduces the influence of the slice profile imperfections of theexcitation purse by keeping the background tissue at the slice edge saturated. Analytical calculations and in vitro experiments show that a prepulse angle of 110 degrees -130 degrees and a delay time of 20-25 ms enhance the contrast between contrast-enhanced blood (T-1 < 50 ms) and background tissues (T-1 > 200 ms), and improve the slice weighting profile. Magnetization preparation is shown to effectively suppress signal from background tissue, resulting in a threefold increase of the vessel-to-background signal ratio. Magnetization preparation eliminates the need for subtraction at the cost of a slight increase in scan time. Possible applications, such as projection MRA, detection of contrast arrival, and test-bolus tracking are demonstrated in a pig model. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 12:21:06