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Titolo:
Normal retinal nerve fiber layer thickness in the peripapillary region measured by scanning laser polarimetry
Autore:
Iester, M; Mermoud, A;
Indirizzi:
Hop Ophtalm Jules Gonin, Lausanne, Switzerland Hop Ophtalm Jules Gonin Lausanne Switzerland nin, Lausanne, Switzerland Univ Genoa, DNVS, Genoa, Italy Univ Genoa Genoa ItalyUniv Genoa, DNVS, Genoa, Italy G Gaslini Inst, Ophthalm Div, Genoa, Italy G Gaslini Inst Genoa ItalyG Gaslini Inst, Ophthalm Div, Genoa, Italy
Titolo Testata:
JOURNAL OF GLAUCOMA
fascicolo: 3, volume: 10, anno: 2001,
pagine: 170 - 176
SICI:
1057-0829(200106)10:3<170:NRNFLT>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
TOPOGRAPHIC MEASUREMENTS; TOMOGRAPHIC SCANNER; CLINICAL-EVALUATION; REPRODUCIBILITY; HEAD; GLAUCOMA; HEALTHY; EYES;
Keywords:
ganglion cell; glaucoma; optic disc; retinal nerve fiber layer thickness; scanning laser polarimetry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Iester, M V Teano 71-1, I-16147 Genoa, Italy V Teano 71-1 Genoa Italy I-16147 no 71-1, I-16147 Genoa, Italy
Citazione:
M. Iester e A. Mermoud, "Normal retinal nerve fiber layer thickness in the peripapillary region measured by scanning laser polarimetry", J GLAUCOMA, 10(3), 2001, pp. 170-176

Abstract

Purpose: To measure retinal nerve fiber layer thickness (RNFLT) as a function of distance from the optic nerve head using a confocal scanning laser polarimeter, such as the Nerve Fiber Analyzer (GDx). Methods: Twenty eyes of 20 healthy patients were recruited for this study. Each patient had a normal visual field and a healthy optic nerve head, which was assessed by slit-lamp biomicroscopy using a 90-diopter lens and by ascanning laser ophthalmoscope. Using the GDx, RNFLT was calculated from 1.1 disc diameters (DD) to 2.5 DD in 0.1-DD increments from the outer edge ofthe optic disc rim. RNFLT was successively evaluated for the entire annulus surface, for each quadrant, and for every 10 degrees sector. RNFLT was calculated in retardation degrees. Differences in RNFLT were calculated by analysis of variance. Results: When the entire RNFLT was considered, the measurements close to the optic nerve head (at 1.1 and 1.2 DD) were found to be significantly (0.05 less than or equal to P less than or equal to 0.01) different from those measured far from the disc (at 2.4 and 2.5 DD). The inferior quadrant had the greatest RNFLT followed by the superior quadrant. When RNFLT was analyzed for every 10 degrees, RNFLT at 1.1 and 1.2 DD was significantly (P less than or equal to 0.001) different from that measured at 2.4 and 2.5 DD in almost all 36 sectors. In the 36 considered sectors, no significant difference was found for all the RNFLT values that were calculated in all the positions of the annulus surface between 1.1 and 1.7 DD. Conclusion: From these data, peripapillary RNFLT is shown to be significantly (P 0.001) thinner in the periphery (2.5 DD) than around the optic disc (1.1 DD). However, the lack of any difference in RNFLT from 1.1 to 1.7 DD suggested that the mild variations to locate the optic disc contour line do not change the results of the analysis if the RNFLT is calculated within 1.8 DD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 20:10:21