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Titolo:
Update and recommendations for the use of antipsychotics in early-onset psychoses
Autore:
Bryden, KE; Carrey, NJ; Kutcher, SP;
Indirizzi:
Dalhousie Univ, Dept Psychiat, AJLB, Halifax, NS B3H 2E2, Canada DalhousieUniv Halifax NS Canada B3H 2E2 JLB, Halifax, NS B3H 2E2, Canada
Titolo Testata:
JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
fascicolo: 2, volume: 11, anno: 2001,
pagine: 113 - 130
SICI:
1044-5463(200122)11:2<113:UARFTU>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
FIRST-EPISODE SCHIZOPHRENIA; DOUBLE-BLIND; CHILDHOOD-ONSET; ADOLESCENT-PSYCHIATRY; RISPERIDONE TREATMENT; TARDIVE-DYSKINESIA; NEGATIVE SYMPTOMS; OLANZAPINE TRIAL; OPEN-LABEL; CHILDREN;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
93
Recensione:
Indirizzi per estratti:
Indirizzo: Kutcher, SP Dalhousie Univ, Dept Psychiat, AJLB, 5909 Vet Mem Lane,9th Floor, Halifax,NS B3H 2E2, Canada Dalhousie Univ 5909 Vet Mem Lane,9th Floor Halifax NS Canada B3H 2E2
Citazione:
K.E. Bryden et al., "Update and recommendations for the use of antipsychotics in early-onset psychoses", J CH AD PSY, 11(2), 2001, pp. 113-130

Abstract

A review was undertaken of studies evaluating the efficacy and tolerability of antipsychotic medications for the management of psychosis in children and adolescents. All identified published and unpublished studies from 1996onward were included for review. The search located one randomized controltrial, seven open-label trials, six retrospective chart reviews, and nine case reports. The studies assessed the use of haloperidol, clozapine, risperidone, olanzapine, and quetiapine in the management of psychosis in children and adolescents. Most studies reported reasonable treatment response; however, extrapyramidal side effects, sedation, and weight gain are concerning. This points to the need for appropriate baseline assessments prior to initiating treatment with these agents. Particular attention should be given to assessment of the extrapyramidal system as well as to baseline weight, lipid profile, and blood glucose. Further study is needed to refine the use of antipsychotic medications in children and adolescents in order to minimize adverse effects while conferring an optimum therapeutic response. The importance of instituting effective early treatment in youth with psychoses is an important goal that may serve to lessen the long-term morbidity of theillness.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 15:52:49