Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Bone turnover and density in obese premenopausal women during moderate weight loss and calcium supplementation
Autore:
Shapses, SA; Von Thun, NL; Heymsfield, SB; Ricci, TA; Ospina, M; Pierson, RN; Stahl, T;
Indirizzi:
Rutgers State Univ, Dept Nutr Sci, New Brunswick, NJ 08901 USA Rutgers State Univ New Brunswick NJ USA 08901 New Brunswick, NJ 08901 USA Columbia Univ, St Lukes Roosevelt Hosp, New York Obes Res Ctr, New York, NY USA Columbia Univ New York NY USA p, New York Obes Res Ctr, New York, NY USA Columbia Univ, St Lukes Roosevelt Hosp, Body Composit Unit, New York, NY USA Columbia Univ New York NY USA Hosp, Body Composit Unit, New York, NY USA Robert Wood Johnson Univ Hosp, Dept Radiol, New Brunswick, NJ USA Robert Wood Johnson Univ Hosp New Brunswick NJ USA New Brunswick, NJ USA
Titolo Testata:
JOURNAL OF BONE AND MINERAL RESEARCH
fascicolo: 7, volume: 16, anno: 2001,
pagine: 1329 - 1336
SICI:
0884-0431(200107)16:7<1329:BTADIO>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
MINERAL DENSITY; BIOCHEMICAL MARKERS; SEASONAL-VARIATION; HEALTHY-SUBJECTS; HIP FRACTURE; RISK-FACTORS; BODY-FAT; MASS; AGE; OSTEOPOROSIS;
Keywords:
bone; bone turnover; calcium; premenopausal; weight loss;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Shapses, SA Rutgers State Univ, Dept Nutr Sci, 96 Lipman Dr, New Brunswick, NJ 08901 USA Rutgers State Univ 96 Lipman Dr New Brunswick NJ USA 08901 USA
Citazione:
S.A. Shapses et al., "Bone turnover and density in obese premenopausal women during moderate weight loss and calcium supplementation", J BONE MIN, 16(7), 2001, pp. 1329-1336

Abstract

Bone turnover is increased during weight loss in postmenopausal women and can be suppressed with calcium supplementation. In this study, we assessed the influence of energy restriction with and without calcium supplementation (1 g/day) in premenopausal women, Thirty-eight obese premenopausal women (body mass index [BMI] of 35.0 +/- 3.9 kg/m(2)) completed a 6-month study of either moderate weight loss or weight maintenance. During weight loss, women were randomly assigned to either a calcium supplementation (n = 14) or placebo group (n = 14) and lost 7.5 +/- 2.5% of their body weight. The control group of women (Iz 10) maintained their body weight. Total body and lumbar bone mineral density (LBMD) and content were measured by dual-energy X-ray absorptiometry (DXA) at baseline and after weight loss. Throughout the study, blood and urine samples were collected to measure bone turnover markers and hormones. During moderate energy restriction, dietary calcium intake decreased (p < 0.05) and the bone resorption marker deoxypyridinoline (DPD) increased slightly (p < 0.05) without evidence of bone loss. Calcium supplementation during weight loss tended to increase lumbar BMD by 1.7% (p = 0.05) compared with the placebo or weight maintenance groups. In contrast to our previous findings in postmenopausal women, premenopausal obese women who consume a low calcium diet do not lose bone over a 6-month period, whether their weight is stable or decreasing moderately.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 18:35:29