Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Embryo selection by the first cleavage parameter between 25 and 27 hours after ICSI
Autore:
Petersen, CG; Mauri, AL; Ferreira, R; Baruffi, RLR; Franco, JG;
Indirizzi:
Sinha Junqueira Matern Fdn, Ctr Human Reprod, BR-14085100 Ribeirao Preto, SP, Brazil Sinha Junqueira Matern Fdn Ribeirao Preto SP Brazil BR-14085100BC Brazil
Titolo Testata:
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
fascicolo: 4, volume: 18, anno: 2001,
pagine: 209 - 212
SICI:
1058-0468(200104)18:4<209:ESBTFC>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACYTOPLASMIC SPERM INJECTION; IN-VITRO FERTILIZATION; INVITRO FERTILIZATION; PREGNANCY RATES; 2-CELL STAGE; QUALITY; INDICATOR; MORPHOLOGY; VIABILITY; PROGRAM;
Keywords:
embryo selection; first cleavage; ICSI; implantation rate; pregnancy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Franco, JG Rua D Alberto Goncalves 1500, BR-14085100 Ribeirao Preto, SP, Brazil Rua D Alberto Goncalves 1500 Ribeirao Preto SP Brazil BR-14085100 BC
Citazione:
C.G. Petersen et al., "Embryo selection by the first cleavage parameter between 25 and 27 hours after ICSI", J AS REPROD, 18(4), 2001, pp. 209-212

Abstract

Purpose: The objective of this study was to assess first embryo cleavage (FEC) 25-27 h after intracytoplasmic sperm injection (ICSI) as a parameter for the embryo selection process. Methods: From January 1998 to December 1999, a total of 670 patients were subjected to the ICSI programme at the Centre for Human Reproduction, SinhaJunqueira Maternity Foundation, and the FEC parameter was evaluated in three situations. Results In the first, a total of 300 zygotes were analyzed on the basis ofa score (16-18 h after ICSI) and observed for the presence or absence of FEC (25-27 h after ICSI). A significant (p < 0.02)presence of FEC was observed in zygotes with a score of 15 (ideal score). In the second a total of 200 patients were selected and divided into two groups matched for age and laboratory performance. Group I (n = 100) was subjected to transfer of embryos with the absence of FEC only (since in this cycle no embryos with FEC were detected within 25-27 h after ICSI) and Group II (n = 100) was subjected to transfer of embryos with the presence of FEC only The age of Group I patients (33.8 +/- 4.2 years) did not differ significantly (p = 0.50) from that of Group II patients (33.5 +/- 4.3 years). The number of embryos transferred was similar (p = 0.07) for Group I (2.7 +/- 1.1) and Group II (2.9 +/- 0.88). In Group II, the 17.5% implantation rate was significantly higher (p< 0.01) than the 5.9% rate obtained for Group I. The pregnancy rate for Group II was significantly higher (p < 0.01) (33%) than that for Group I (12%). The incidence of abortion was 16.6% in Group I as compared with 6% in Group II lit the third situation, we observed the frequency of embryos with FEC in 36 patients whose implantation rate was 100% (ideal result) and obtained a value of 82%. Conclusions The data suggest that the presence of the FEC parameter that was evaluated 25-27 h after ICSI could be used to select embryos with a higher implantation power. The data reported here may justify routine analysis of embryos with FEC for the process of embryo selection after ICSI.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 04:23:18