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Titolo:
Effect of morning exercise on counterregulatory responses to subsequent, afternoon exercise
Autore:
Galassetti, P; Mann, S; Tate, D; Neill, RA; Wasserman, DH; Davis, SN;
Indirizzi:
Vanderbilt Univ, Sch Med, Div Diabet & Endocrinol, Dept Med, Nashville, TN37232 USA Vanderbilt Univ Nashville TN USA 37232 , Dept Med, Nashville, TN37232 USA Vanderbilt Univ, Sch Med, Dept Physiol & Mol Biophys, Nashville, TN 37232 USA Vanderbilt Univ Nashville TN USA 37232 l Biophys, Nashville, TN 37232 USA Nashville Vet Affairs Med Ctr, Nashville, TN 37232 USA Nashville Vet Affairs Med Ctr Nashville TN USA 37232 hville, TN 37232 USA
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 1, volume: 91, anno: 2001,
pagine: 91 - 99
SICI:
8750-7587(200107)91:1<91:EOMEOC>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUCOSE COUNTERREGULATION; ANTECEDENT HYPOGLYCEMIA; METABOLIC RESPONSES; HORMONAL RESPONSES; DIABETES-MELLITUS; STRESS HORMONES; REPEATED BOUTS; INSULIN; GENDER; GLUCAGON;
Keywords:
glucose clamp; epinephrine; glucagon;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Galassetti, P Vanderbilt Univ, Sch Med, Div Diabet & Endocrinol, Dept Med,712 PRB, Nashville, TN 37232 USA Vanderbilt Univ 712 PRB Nashville TN USA 37232 TN 37232 USA
Citazione:
P. Galassetti et al., "Effect of morning exercise on counterregulatory responses to subsequent, afternoon exercise", J APP PHYSL, 91(1), 2001, pp. 91-99

Abstract

The aim of this study was to determine whether a bout of morning exercise (EXE1) can alter neuroendocrine and metabolic responses to subsequent afternoon exercise (EXE2) and whether these changes follow a gender-specific pattern. Sixteen healthy volunteers (8 men and 8 women, age 27 +/- 1 yr, body mass index 23 +/- 1 kg/m(2), maximal O-2 uptake 31 +/- 2 ml.kg(-1).min(-1))were studied after an overnight fast. EXE1 and EXE2 each consisted of 90 min of cycling on a stationary bike at 48 +/- 2% of maximal O-2 uptake separated by 3 h. To avoid the confounding effects of hypoglycemia and glycogen depletion, carbohydrate (1.5 g/kg body wt po) was given after EXE1, and plasma glucose was maintained at euglycemia during both episodes of exercise by a modification of the glucose-clamp technique. Basal insulin levels (7 +/- 1 muU/ml) and exercise-induced insulin decreases (-3 muU/ml) were similarduring EXE1 and EXE2. Plasma glucose was 5.2 +/- 0.1 and 5.2 +/- 0.1 mmol/l during EXE1 and EXE2, respectively. The glucose infusion rate needed to maintain euglycemia during the last 30 min of exercise was increased during EXE2 compared with EXE1 (32 +/- 4 vs. 7 +/- 2 mu mol.kg(-1).min(-1)). Although this increased need for exogenous glucose was similar in men and women,gender differences in counterregulatory responses were significant. Compared with EXE1, epinephrine, norepinephrine, growth hormone, pancreatic polypeptide, and cortisol responses were blunted during EXE2 in men, but neuroendocrine responses were preserved or increased in women. In summary, morningexercise significantly impaired the body's ability to maintain euglycemia during later exercise of similar intensity and duration. We conclude that antecedent exercise can significantly modify, in a gender-specific fashion, metabolic and neuroendocrine responses to subsequent exercise.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 06:45:33