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Titolo:
Bladder-sphincter dysfunction in myelomeningocele
Autore:
van Gool, JD; Dik, P; de Jong, TPVM;
Indirizzi:
Wilhelmina Kinderziekenhuis, Paediatr Renal Ctr, WKZ, NL-3508 AB Utrecht, Netherlands Wilhelmina Kinderziekenhuis Utrecht Netherlands NL-3508 AB , Netherlands
Titolo Testata:
EUROPEAN JOURNAL OF PEDIATRICS
fascicolo: 7, volume: 160, anno: 2001,
pagine: 414 - 420
SICI:
0340-6199(200107)160:7<414:BDIM>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRAVESICAL OXYBUTYNIN CHLORIDE; INTERMITTENT CATHETERIZATION; NEUROGENIC BLADDER; SPINA-BIFIDA; VESICOURETERAL REFLUX; NEUROPATHIC BLADDER; URINARY-DIVERSION; CHILDREN; MYELODYSPLASIA; MANAGEMENT;
Keywords:
myelomeningocele; neuropathic bladder-sphincter dysfunction detrusor-sphincter dyssynergia; clean intermittent catheterization; anticholinergics; bladder compliance; bladder capacity; obstructive uropathy; urodynamics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: van Gool, JD Wilhelmina Kinderziekenhuis, Paediatr Renal Ctr, WKZ, POB 85090, NL-3508 AB Utrecht, Netherlands Wilhelmina Kinderziekenhuis POB 85090 Utrecht Netherlands NL-3508 AB
Citazione:
J.D. van Gool et al., "Bladder-sphincter dysfunction in myelomeningocele", EUR J PED, 160(7), 2001, pp. 414-420

Abstract

Pediatric urodynamics taught us that detrusor-sphincter dyssynergia creates a bladder outlet obstruction in about 50% of any population of children with myelomeningocele. This functional obstruction causes renal damage due to obstructive uropathy, exactly the same way as a congenital anatomical urethral obstruction does. Pediatric urodynamics also taught us that in children with myelomeningocele pelvic floor activity and detrusor activity can beabnormal (hyperactive or inactive) completely independent from each other. These insights have changed the management of myelomeningocele. Children with overactivity of the pelvic floor can be singled out at infant age, and started on clean intermittent catherization, to prevent obstructive uropathy and preserve renal function. Children with detrusor overactivity can be singled out too at very early age, and treated with anticholinergics, to prevent irreversible structural damage to the detrusor and preserve normal bladder capacity and compliance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 09:14:34