Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Early alterations of blood pressure in normotensive and normoalbuminuric Type 1 diabetic patients
Autore:
Cohen, CN; Albanesi, FM; Goncalves, MD; Gomes, MD;
Indirizzi:
State Univ Hosp Rio de Janeiro, Dept Med, Unit Cardiol, BR-20551030 Rio DeJaneiro, Brazil State Univ Hosp Rio de Janeiro Rio De Janeiro Brazil BR-20551030 BCrazil State Univ Hosp Rio de Janeiro, Dept Med, Diabet Unit, BR-20551030 Rio De Janeiro, Brazil State Univ Hosp Rio de Janeiro Rio De Janeiro Brazil BR-20551030 BCrazil
Titolo Testata:
DIABETES RESEARCH AND CLINICAL PRACTICE
fascicolo: 2, volume: 53, anno: 2001,
pagine: 85 - 90
SICI:
0168-8227(200108)53:2<85:EAOBPI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
IDDM PATIENTS; ESSENTIAL-HYPERTENSION; AUTONOMIC NEUROPATHY; NON-DIPPERS; MELLITUS; MICROALBUMINURIA; ABNORMALITIES; ADOLESCENTS; NEPHROPATHY; INSULIN;
Keywords:
ambulatory blood pressure monitoring; normoalbuminuria; Type 1 diabetes;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Cohen, CN Cesar Nissan Cohen-Rua Dona Romana 621, BR-20710200 Rio De Janeiro, Brazil Cesar Nissan Cohen-Rua Dona Romana 621 Rio De Janeiro Brazil BR-20710200 BC
Citazione:
C.N. Cohen et al., "Early alterations of blood pressure in normotensive and normoalbuminuric Type 1 diabetic patients", DIABET RE C, 53(2), 2001, pp. 85-90

Abstract

With the objective to examine patterns of blood pressure (BP) in normotensive and normoalbuminuric Type 1 diabetic patients during 24 h ambulatory blood pressure monitoring (ABPM) we studied 28 Type 1 diabetic patients aged 27 +/-7.1 years with a disease duration of 9 +/-6.6 years, and 28 non-diabetic normotensive subjects aged 25 +/-6.5 years matched to the diabetic group For age, Sender, skin color, weight, height, body mass index, clinic BP and absence of microalbuminuria. Systolic BP (sBP) and diastolic BP (dBP) were recorded for 24 h, daytime and nighttime. SEP and dBP burden, night/day BP ratios and percent nighttime BP fall were determined. Subjects with a nocturnal fall in either sBP or dBP of less than 10% of daytime values were classified as non-dippers. Both sBP (111 +/-7.1 vs. 103 +/-9 mmHg; P = 0.003) and dBP nighttime (66 +/-6.1 vs. 61 +/-5.3 mmHg; P = 0.001) were higher in diabetic patients than non-diabetic subjects. Night/day ratios for sBP (0.93 +/-0.04 vs. 0.89 +/-0.05; P = 0.006) and dBP (0.86 +/-0.06 vs. 0.82 +/-0.06; P = 0.007) were higher in diabetics. The loss of a fall in sBP was more prevalent in diabetic subjects (78 vs. 39%; P = 0.007). Non-dippers for sBP and dBP in the diabetic group had higher BP burden during the nighttime(21.4 +/- 16.6 vs. 3.2 +/-3.9%; P = 0.01 and 21.9 +/- 10 vs. 3.7 +/-5.5%; P<0.001, respectively). Our data demonstrate hight I sBP and dBP during thenighttime and loss of the nocturnal fall in BP in Type 1 diabetic patients. Further prospective studies ale needed to define if high BP burden in diabetic non-dippers Juring the night could represent a risk for nephropathy and cardiovascular disease. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 21:45:54