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Titolo:
The use of granulocyte colony-stimulating factor for treatment of autoimmune neutropenia
Autore:
Smith, MA; Smith, JG;
Indirizzi:
Royal United Hosp, Dept Hematol, Bath BA1 3NG, Avon, England Royal United Hosp Bath Avon England BA1 3NG , Bath BA1 3NG, Avon, England Univ W England, Ctr Res Biomed Sci, Bristol BS16 1QY, Avon, England Univ WEngland Bristol Avon England BS16 1QY stol BS16 1QY, Avon, England Univ W England, Fac Sci Appl, Bristol BS16 1QY, Avon, England Univ W England Bristol Avon England BS16 1QY stol BS16 1QY, Avon, England
Titolo Testata:
CURRENT OPINION IN HEMATOLOGY
fascicolo: 3, volume: 8, anno: 2001,
pagine: 165 - 169
SICI:
1065-6251(200105)8:3<165:TUOGCF>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEVERE CONGENITAL NEUTROPENIA; ACUTE MYELOID-LEUKEMIA; G-CSF; FACTOR-RECEPTOR; MUTATIONS; INFANCY; AGRANULOCYTOSIS; MYELODYSPLASIA; SURVIVAL; THERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Smith, JG Royal United Hosp, Dept Hematol, Combe Pk, Bath BA1 3NG, Avon, England Royal United Hosp Combe Pk Bath Avon England BA1 3NG on, England
Citazione:
M.A. Smith e J.G. Smith, "The use of granulocyte colony-stimulating factor for treatment of autoimmune neutropenia", CURR OPIN H, 8(3), 2001, pp. 165-169

Abstract

The advent of better diagnostic tools, molecular techniques, and cytokine therapies have come together at the end of the 20th century to provide an improved outlook for patients with autoimmune neutropenia, Severe chronic neutropenia is no longer idiopathic in most cases, and growth factor therapy can be safely offered to selected patient groups. Previously unsuccessful and even dangerous forms of treatment are no longer appropriate, and G-CSF treatment appears to be safe when administered long term. Fears about transformation of these disorders into acute myeloblastic leukemia probably relate to the underlying natural history of these disorders rather than to theirtreatment. (C) 2001 Lippincott Williams & Wilkins, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 15:57:53