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Titolo:
Critical care medicine in the 21st century: from CPR to PCR
Autore:
Villar, J; Mendez, S; Slutsky, AS;
Indirizzi:
Hosp Candelaria, Res Inst, Mol Biol Lab, Tenerife, Canary Islands, Spain Hosp Candelaria Tenerife Canary Islands Spain ife, Canary Islands, Spain Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada Mt Sinai Hosp Toronto ON Canada M5G 1X5 Hosp, Toronto, ON M5G 1X5, Canada Mercer Univ, Macon, GA 31207 USA Mercer Univ Macon GA USA 31207Mercer Univ, Macon, GA 31207 USA Univ La Laguna, Dept Microbiol & Cell Biol, Tenerife, Canary Islands, Spain Univ La Laguna Tenerife Canary Islands Spain rife, Canary Islands, Spain Univ Toronto, Toronto, ON, Canada Univ Toronto Toronto ON CanadaUniv Toronto, Toronto, ON, Canada St Michaels Hosp, Toronto, ON M5B 1W8, Canada St Michaels Hosp Toronto ONCanada M5B 1W8 p, Toronto, ON M5B 1W8, Canada
Titolo Testata:
CRITICAL CARE
fascicolo: 3, volume: 5, anno: 2001,
pagine: 125 - 130
SICI:
1466-609X(2001)5:3<125:CCMIT2>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS-SYNDROME; TUMOR-NECROSIS-FACTOR; POLYMERASE-CHAIN-REACTION; SYSTEM ORGAN FAILURE; MECHANICAL VENTILATION; RNA EXPRESSION; LUNG; INTERLEUKIN-10; MORTALITY; CYTOKINES;
Keywords:
acute respiratory failure; critically ill patients; intensive care medicine; molecular biology; molecular medicine;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Villar, J Hosp Candelaria, Res Inst, Carretera Rosario S-N, Santa Cruz De Tenerife 38010, Canary Islands, Spain Hosp Candelaria Carretera Rosario S-NSanta Cruz De Tenerife Canary Islands Spain 38010
Citazione:
J. Villar et al., "Critical care medicine in the 21st century: from CPR to PCR", CRIT CARE, 5(3), 2001, pp. 125-130

Abstract

As in other areas of medicine, the specialty of critical care medicine, which has made important contributions in the pathophysiology of critical illness, is facing challenges that must be recognized and addressed in the current century. In this review, we argue that the skill set required to adequately treat critically ill patients will also require knowledge of molecular biology for better diagnosis and treatment. The foundations of molecular biology and genetics are essential for the understanding of the mechanisms of disease. Incorporating molecular biology techniques in the research arsenal of the intensivist will provide the opportunity to dissect out and define the reversible and irreversible intracellular processes giving rise to the major causes of mortality in intensive care units. Two historical paradigms, the cardiopulmonary resuscitation and polymerase chain reaction, summarize how critical care medicine began, and how it could mature in the yearsto come.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 00:40:02