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Titolo:
The histologic estimation of coronary artery stenoses: Accuracy and the effect of lumen shape
Autore:
Ford, JC; ORourke, K; Veinot, JP; Walley, VM;
Indirizzi:
Peterborough Reg Hlth Ctr, Dept Lab Med, Peterborough, ON K9J 7C6, Canada Peterborough Reg Hlth Ctr Peterborough ON Canada K9J 7C6 K9J 7C6, Canada Univ Ottawa, Dept Pathol & Lab Med, Ottawa, ON K1H 8M5, Canada Univ Ottawa Ottawa ON Canada K1H 8M5 Lab Med, Ottawa, ON K1H 8M5, Canada Univ Ottawa, Loeb Hlth Res Inst, Clin Epidemiol Unit, Ottawa, ON K1Y 4E9, Canada Univ Ottawa Ottawa ON Canada K1Y 4E9 iol Unit, Ottawa, ON K1Y 4E9, Canada Univ Ottawa, Dept Surg, Ottawa, ON K1H 8M5, Canada Univ Ottawa Ottawa ON Canada K1H 8M5 ept Surg, Ottawa, ON K1H 8M5, Canada
Titolo Testata:
CARDIOVASCULAR PATHOLOGY
fascicolo: 2, volume: 10, anno: 2001,
pagine: 91 - 96
SICI:
1054-8807(200103/04)10:2<91:THEOCA>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
REPRODUCIBILITY; RELIABILITY;
Keywords:
coronary artery; histology; atherosclerosis; accuracy; image analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Walley, VM Peterborough Reg Hlth Ctr, Dept Lab Med, 1 Hosp Dr, Peterborough, ON K9J 7C6, Canada Peterborough Reg Hlth Ctr 1 Hosp Dr Peterborough ON Canada K9J 7C6
Citazione:
J.C. Ford et al., "The histologic estimation of coronary artery stenoses: Accuracy and the effect of lumen shape", CARDIO PATH, 10(2), 2001, pp. 91-96

Abstract

The authors have recently investigated the histologic estimation of coronary artery stenoses (CAS) to determine its reproducibility and the effect oftraining on reproducibility. The present study extends this work, examining the accuracy, the sensitivity, and the specificity of the estimation of GAS. Further, the effect of one histologic variable (i.e., arterial lumen shape) on the evaluation of CAS is examined. As described previously, 20 randomly selected Movat-stained coronary artery cross-sections were reviewed three times, at 3-month intervals, by six clinical pathologists (CPs), six pathology residents (Res), seven anatomic pathologists (APs), and two cardiovascular pathologists (CVPs). Before the third iteration, training in CAS assessment was provided. In the present study, for comparison with observer estimates, image analysis was used to establish the actual percent CAS and determine observer accuracy. The results of this study showed, paradoxically, that greater experience did not correlate with greater accuracy: The CPs consistently had the highest accuracy scores and the CVPs consistently had the lowest. Training, however, improved the accuracy scores of all groups. Stenotic arterial cross-sections with residual lumens showing concentric oreccentric polymorphous shapes were consistently underestimated compared toimage analysis, while lumens with a eccentric slitlike shape were consistently overestimated. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 15:38:04