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Titolo:
Differential coronary artery calcification detected by electron beam computed tomography as an indicator of coronary stenosis among patients with stable angina pectoris
Autore:
Chen, LC; Chen, JW; Wu, MH; Liu, JC; Lan, GY; Wu, TC; Chern, MS; Chang, CY; Chang, MS; Ding, PYA;
Indirizzi:
Taichung Vet Gen Hosp, Dept Med, Div Cardiol, Sect 2,Shih Pai Rd, Taipei, Taiwan Taichung Vet Gen Hosp Taipei Taiwan Sect 2,Shih Pai Rd, Taipei, Taiwan Cheng Hsin Gen Hosp, Dept Med Imaging, Taipei, Taiwan Cheng Hsin Gen HospTaipei Taiwan osp, Dept Med Imaging, Taipei, Taiwan Affiliated Taipei Wan Fang Hosp, Taipei, Taiwan Affiliated Taipei Wan FangHosp Taipei Taiwan Fang Hosp, Taipei, Taiwan Taipei Med Univ, Div Cardiovasc Med, Taipei, Taiwan Taipei Med Univ Taipei Taiwan Univ, Div Cardiovasc Med, Taipei, Taiwan Taichung Vet Gen Hosp, Dept Radiol, Taipei, Taiwan Taichung Vet Gen Hosp Taipei Taiwan n Hosp, Dept Radiol, Taipei, Taiwan Natl Yang Ming Univ, Sch Med, Cardiovasc Res Ctr, Taipei 112, Taiwan Natl Yang Ming Univ Taipei Taiwan 112 iovasc Res Ctr, Taipei 112, Taiwan
Titolo Testata:
CANADIAN JOURNAL OF CARDIOLOGY
fascicolo: 6, volume: 17, anno: 2001,
pagine: 667 - 676
SICI:
0828-282X(200106)17:6<667:DCACDB>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; INTRAVASCULAR ULTRASOUND; CHEST PAIN; LUMEN STENOSIS; CALCIUM; EXERCISE; DISEASE; PLAQUE; ATHEROSCLEROSIS; QUANTIFICATION;
Keywords:
arteries; atherosclerosis; calcification; coronary disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Ding, PYA Taichung Vet Gen Hosp, Dept Med, Div Cardiol, Sect 2,Shih Pai Rd, 112,201,Taipei, Taiwan Taichung Vet Gen Hosp 112,201 Taipei Taiwan 201,Taipei, Taiwan
Citazione:
L.C. Chen et al., "Differential coronary artery calcification detected by electron beam computed tomography as an indicator of coronary stenosis among patients with stable angina pectoris", CAN J CARD, 17(6), 2001, pp. 667-676

Abstract

BACKGROUND: The detection of coronary artery calcification by electron beam computed tomography (EBCT) has been suggested as an indicator of atherosclerosis and coronary artery disease (CAD). There is no consensus on the correlation between coronary calcification and angiographically significant stenosis on an artery-by-artery basis. OBJECTIVE: To examine the relationship between coronary calcification score (CCS) and the presence of significant CAD on an artery-by-artery basis inpatients with stable angina pectoris. METHODS AND RESULTS: EBCT and coronary angiogram (CAG) were evaluated in 71 patients with stable angina and in nine control subjects. The CCSs of each of the four major coronary arteries were highest in patients with significant CAD (n=43), followed by patients with insignificant CAD (n=5), patients with syndrome X (n=23) and control subject, respectively. Calcification scores of the four major coronary arteries appeared to have different predictive power for significant stenosis on the same vessel. For left main (LM) anal left anterior descending (LAD) coronary arteries, CCSs of vessels withsignificant stenoses were not different from those without significant stenoses (values expressed as medians: LM 0 versus1; LAD 98.5 versus 70; not significant). Calcification scores of left circumflex (LCX) and right coronary arteries (RCA) were significantly higher in vessels with significant stenosis (LCX 49.5 versus 0; RCA 53 versus 1; P <0.05). CCSs appeared to be moderately useful to predict significant stenoses in these two vessels (areasunder receiver operating characteristic curves: LCX 0.68 +/-0.08, 95%, CI 0.52 to 0.81; RCA 0.71 +/-0.08, 95% CI 0.55 to 0.84). CONCLUSIONS: The CCSs or RCA and LCX arteries, but not those of LM and LADarteries, may predict significant angiographic stenosis on an artery-by-artery basis among patients with stable angina pectoris.

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Documento generato il 06/04/20 alle ore 01:24:32