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Titolo:
Prepulse effects as a function of cortical projection system
Autore:
Perlstein, WM; Simons, RF; Graham, FK;
Indirizzi:
Univ Florida, Hlth Sci Ctr, Dept Clin & Hlth Psychol, Gainesville, FL 32610 USA Univ Florida Gainesville FL USA 32610 Psychol, Gainesville, FL 32610 USA Univ Florida, Hlth Sci Ctr, Dept Psychiat, Gainesville, FL 32610 USA Univ Florida Gainesville FL USA 32610 Psychiat, Gainesville, FL 32610 USA Univ Florida, Hlth Sci Ctr, McKnight Brain Inst, Gainesville, FL 32610 USAUniv Florida Gainesville FL USA 32610 ain Inst, Gainesville, FL 32610 USA Univ Delaware, Dept Psychol, Newark, DE 19716 USA Univ Delaware Newark DEUSA 19716 are, Dept Psychol, Newark, DE 19716 USA
Titolo Testata:
BIOLOGICAL PSYCHOLOGY
fascicolo: 2, volume: 56, anno: 2001,
pagine: 83 - 111
SICI:
0301-0511(200105)56:2<83:PEAAFO>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUDITORY-EVOKED-POTENTIALS; ACOUSTIC STARTLE RESPONSE; STIMULATION INTERVAL; MAGNITUDE ESTIMATION; STIMULUS-INTENSITY; LOUDNESS JUDGMENTS; VERTEX RESPONSE; MAGNETIC-FIELDS; P50 SUPPRESSION; BRAIN-STEM;
Keywords:
prepulse inhibition; startle; P30; P50; N100; auditory event-related potentials; magnitude estimation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
95
Recensione:
Indirizzi per estratti:
Indirizzo: Perlstein, WM Univ Florida, Hlth Sci Ctr, Dept Clin & Hlth Psychol, POB 100165, Gainesville, FL 32610 USA Univ Florida POB 100165 Gainesville FL USA 32610 L 32610 USA
Citazione:
W.M. Perlstein et al., "Prepulse effects as a function of cortical projection system", BIOL PSYCH, 56(2), 2001, pp. 83-111

Abstract

A putative gating mechanism reduces startle blink, midline scalp potentials beginning with P50, and perceived loudness of startling stimuli. Tactile prestimuli were paired with auditory startle stimuli to determine if: (1) P50 inhibition is due to an extrinsic mechanism, (2) pairing differentially affects potentials reflecting modality specific and nonspecific system activity, and (3) crossmodal pairing modifies perceptual magnitudes of both pair members. Stimuli were presented alone and in pairs separated by 60 or 360ms. Event-related potentials (ERPs) were recorded from midline and lateralsites: E:MC was recorded from several facial and scalp muscles. Pairing reduced blink, and midline F50, N100 and P200 amplitudes; reductions were greater at the longer interval. P30 was largely unaffected by pairing. Pairingalso differentially affected lateral N100 components reflecting later activity in specific and nonspecific systems. Results show that prestimulus inhibition of ERPs is not due to intrinsic refractoriness and that pairing differentially affects ERPs associated with modality specific and nonspecific projection systems. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 16:09:36