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Titolo:
Leptin expression in placental and fetal tissues: does leptin have a functional role?
Autore:
Hoggard, N; Haggarty, P; Thomas, L; Lea, RG;
Indirizzi:
Rowett Res Inst, ACERO, Aberdeen AB21 9SB, Scotland Rowett Res Inst Aberdeen Scotland AB21 9SB , Aberdeen AB21 9SB, Scotland
Titolo Testata:
BIOCHEMICAL SOCIETY TRANSACTIONS
, volume: 29, anno: 2001,
parte:, 2
pagine: 57 - 63
SICI:
0300-5127(200105)29:<57:LEIPAF>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECEPTOR MESSENGER-RNA; TUMOR-NECROSIS-FACTOR; NORMAL FEMALE MICE; SERUM LEPTIN; CORD-BLOOD; ADIPOSE-TISSUE; AMNIOTIC-FLUID; MATERNAL SERUM; PLASMA LEPTIN; PREGNANCY;
Keywords:
leptin receptor; placenta; pregnancy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Hoggard, N Rowett Res Inst, ACERO, Greenburn Rd, Aberdeen AB21 9SB, Scotland Rowett Res Inst Greenburn Rd Aberdeen Scotland AB21 9SB otland
Citazione:
N. Hoggard et al., "Leptin expression in placental and fetal tissues: does leptin have a functional role?", BIOCH SOC T, 29, 2001, pp. 57-63

Abstract

Leptin is expressed in the placenta and in certain fetal tissues; however,little is known with regard to the function of this hormone in these tissues. To date, most evidence suggests that placental and/or fetal leptin actsas a fetal growth factor, but this is far from clear. Leptin may also havephysiological effects on the placenta, including angiogenesis, growth and immunomodulation. The effects of placental leptin, if any, on the mother may contribute to endocrine-mediated alterations in energy balance, such as the mobilization of maternal fat, which occurs during the second half of pregnancy. In this review we will address these and other issues related to the expression of both placental and fetal leptin.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:32:27