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Titolo:
Surgical results of skull base surgery for the treatment of head and neck malignancies involving skull base: multi-institutional studies on 143 casesin Japan
Autore:
Fukuda, S; Sakai, N; Kamata, SE; Nameki, H; Kishimoto, S; Nishikawa, K; Kaneko, S; Miyata, M; Fujii, M; Inuyama, Y;
Indirizzi:
Hokkaido Univ, Sch Med, Dept Otolaryngol, Kita Ku, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Sapporo Hokkaido Japan 0608638 oro, Hokkaido 0608638, Japan Canc Inst Hosp, Div Head & Neck, Tokyo 0028072, Japan Canc Inst Hosp Tokyo Japan 0028072 Div Head & Neck, Tokyo 0028072, Japan Shizuoka Red Cross Hosp, Dept Otolaryngol, Shizuoka 4200853, Japan Shizuoka Red Cross Hosp Shizuoka Japan 4200853 , Shizuoka 4200853, Japan Tokyo Med & Dent Univ, Sch Med, Dept Head & Neck Surg, Tokyo 1138519, Japan Tokyo Med & Dent Univ Tokyo Japan 1138519 eck Surg, Tokyo 1138519, Japan Shikoku Canc Ctr Hosp, Dept Otolaryngol, Shikoku, Ehime 7900007, Japan Shikoku Canc Ctr Hosp Shikoku Ehime Japan 7900007 u, Ehime 7900007, Japan Toranomon ENT Clin, Tokyo 1050001, Japan Toranomon ENT Clin Tokyo Japan 1050001 on ENT Clin, Tokyo 1050001, Japan Miyata ENT Clin, Utsunomiya, Tochigi 3200851, Japan Miyata ENT Clin Utsunomiya Tochigi Japan 3200851 , Tochigi 3200851, Japan Keio Univ, Sch Med, Dept Otolaryngol, Tokyo 1600016, Japan Keio Univ Tokyo Japan 1600016 ed, Dept Otolaryngol, Tokyo 1600016, Japan
Titolo Testata:
AURIS NASUS LARYNX
, volume: 28, anno: 2001, supplemento:, S
pagine: S71 - S75
SICI:
0385-8146(200105)28:<S71:SROSBS>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Keywords:
skull base surgery; craniofacial resection;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Fukuda, S Hokkaido Univ, Sch Med, Dept Otolaryngol, Kita Ku, Kita 15 Nishi7, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Kita 15 Nishi 7 Sapporo Hokkaido Japan 0608638 pan
Citazione:
S. Fukuda et al., "Surgical results of skull base surgery for the treatment of head and neck malignancies involving skull base: multi-institutional studies on 143 casesin Japan", AURIS NAS L, 28, 2001, pp. S71-S75

Abstract

We analyzed 143 cases of skull base surgery collected from the eight institutions of the Study Group supported by the Grant-in-Aid for Cancer Research from the Ministry of Health and Welfare of Japan. Histologically, the most common type was squamous cell carcinoma (n = 78), which was followed by olfactory neuroblastoma (n = 16) and adenoid cystic carcinoma (n = 16). The most frequent surgical approach was frontal craniotomy (n = 66), followed by front-temporal craniotomy (n = 54) and infratemporal fossa approach (n = 8). For repair of dura matter, fascia lata was used in 37 cases, galeopericranial flap in 35 and temporal muscle fascia in 16. The 5-year survival rate by Kaplan-Meier method of nose and paranasal sinus carcinoma (n = 119) was 48%. As for histological classification, the survival rates were both 65%in adenoid cystic carcinoma (n = 12) and bone soft tissue malignancy (n = 10), 62% in olfactory neuroblastoma (n = 16), 46% in squamous cell carcinoma (n = 62) and 33% in adenocarcinoma (n = 11). All the three cases of malignant melanoma died within 1 year, so we considered skull base surgery to becontraindicated for this disease, Complications were observed in 62 out ofthe 143 cases (43%); local infection was most frequent in 29 cases, liquorrhea in 18, abscess in 16, necrosis of the flap and meningitis in ten cases, DIC in four, rupture of the internal carotid artery in two and cerebral thrombosis in one. Death caused directly by surgery was in ten cases (7%). It is important that a multi-center registry be maintained to have a large enough database for comparison of results, and prognosis for each histological entity and further define the role of multidisciplinary treatment. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 17:28:40