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Titolo:
Relation of sleep-disordered breathing to cardiovascular disease risk factors - The Sleep Heart Health Study
Autore:
Newman, AB; Nieto, FJ; Guidry, U; Lind, BK; Redline, S; Shahar, E; Pickering, TG; Quan, SF;
Indirizzi:
Univ Pittsburgh, Pittsburgh, PA 15213 USA Univ Pittsburgh Pittsburgh PA USA 15213 tsburgh, Pittsburgh, PA 15213 USA Johns Hopkins Univ, Baltimore, MD 21218 USA Johns Hopkins Univ Baltimore MD USA 21218 s Univ, Baltimore, MD 21218 USA Boston Univ, Boston, MA 02215 USA Boston Univ Boston MA USA 02215Boston Univ, Boston, MA 02215 USA Univ Washington, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 iv Washington, Seattle, WA 98195 USA Rainbow Babies & Childrens Hosp, Cleveland, OH 44106 USA Rainbow Babies & Childrens Hosp Cleveland OH USA 44106 land, OH 44106 USA Univ Minnesota, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 nesota, Minneapolis, MN 55455 USA Cornell Univ, Ithaca, NY 14853 USA Cornell Univ Ithaca NY USA 14853Cornell Univ, Ithaca, NY 14853 USA Univ Arizona, Tucson, AZ 85721 USA Univ Arizona Tucson AZ USA 85721Univ Arizona, Tucson, AZ 85721 USA
Titolo Testata:
AMERICAN JOURNAL OF EPIDEMIOLOGY
fascicolo: 1, volume: 154, anno: 2001,
pagine: 50 - 59
SICI:
0002-9262(20010701)154:1<50:ROSBTC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; MYOCARDIAL-INFARCTION; APNEA; ASSOCIATION; MEN; OBESITY; SMOKING; WOMEN;
Keywords:
cardiovascular diseases; respiration; sleep apnea syndromes; sleep disorders;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Newman, AB Univ Pittsburgh, 3520 5th Ave,Suite 300, Pittsburgh, PA 15213 USA Univ Pittsburgh 3520 5th Ave,Suite 300 Pittsburgh PA USA 15213
Citazione:
A.B. Newman et al., "Relation of sleep-disordered breathing to cardiovascular disease risk factors - The Sleep Heart Health Study", AM J EPIDEM, 154(1), 2001, pp. 50-59

Abstract

Associations between sleep-disordered breathing and cardiovascular disease(CVD) may be mediated by higher cardiovascular risk factor levels in thosewith sleep-disordered breathing. The authors examined these relations in the Sleep Heart Health Study, a multiethnic cohort of 6,440 men and women over age 40 years conducted from October 1995 to February 1998 and characterized by home polysomnography. In 4,991 participants who were free of self-reported CVD at the time of the sleep study, moderate levels of sleep-disordered breathing were common, with a median Respiratory Disturbance Index (RDI) of 4.0 (interquartile range, 1.25-10.7). The level of RDI was associated cross-sectionally with age, body mass index, waist-to-hip ratio, hypertension, diabetes, and lipid levels. These relations were more pronounced in those under age 65 years than in those over age 65. Women under age 65 years with RDI in the higher quartiles were more obese than men with similar RDI. Although the pattern of associations was consistent with greater obesity inthose with higher RDI, higher body mass index did not explain all of theseassociations. If sleep-disordered breathing is shown in future follow-up to increase the risk for incident CVD events, part of the risk is likely to be due to the higher cardiovascular risk factors in those with higher RDI.

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Documento generato il 30/11/20 alle ore 16:28:47