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Titolo:
Delivering on the promise of bone morphogenetic proteins
Autore:
Li, RH; Wozney, JM;
Indirizzi:
Inst Genet, Andover, MA 01810 USA Inst Genet Andover MA USA 01810Inst Genet, Andover, MA 01810 USA
Titolo Testata:
TRENDS IN BIOTECHNOLOGY
fascicolo: 7, volume: 19, anno: 2001,
pagine: 255 - 265
SICI:
0167-7799(200107)19:7<255:DOTPOB>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
OSTEOGENIC PROTEIN; IN-VIVO; CLINICAL-EVALUATION; SPINAL ARTHRODESIS; PERIODONTAL REPAIR; NONHUMAN-PRIMATES; TIBIAL FRACTURE; BETA FAMILY; BOVINE BONE; RHBMP-2;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
91
Recensione:
Indirizzi per estratti:
Indirizzo: Li, RH Inst Genet, 1 Burtt Rd, Andover, MA 01810 USA Inst Genet 1 Burtt RdAndover MA USA 01810 d, Andover, MA 01810 USA
Citazione:
R.H. Li e J.M. Wozney, "Delivering on the promise of bone morphogenetic proteins", TRENDS BIOT, 19(7), 2001, pp. 255-265

Abstract

The advent of bone growth factors has been widely anticipated since their successful production using recombinant DNA technology. Bone morphogenetic proteins (BMPs) are an im porta nt class of bone growth factors and will bethe focus of this article. In the near future these therapeutics might revolutionize how clinicians treat such diverse orthopedic applications as thehealing of broken bones, increasing bone density lost th rough aging, and strengthening the spine. These potent proteins require application directlyat the site of repair via a delivery system, The choice of delivery systemhas a profound effect on the clinical outcome. In the past decade, researchers have focused on developing efficient delivery systems and advancing these factors from the bench to the clinic.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 22:02:26