Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Incremental net benefit in randomized clinical trials
Autore:
Willan, AR; Lin, DY;
Indirizzi:
McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON L8P 3A1, CanadaMcMaster Univ Hamilton ON Canada L8P 3A1 at, Hamilton, ON L8P 3A1, Canada St Josephs Hosp, Ctr Evaluat Med, Hamilton, ON L8P 3A1, Canada St Josephs Hosp Hamilton ON Canada L8P 3A1 , Hamilton, ON L8P 3A1, Canada Univ Washington, Dept Biostat, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Dept Biostat, Seattle, WA 98195 USA
Titolo Testata:
STATISTICS IN MEDICINE
fascicolo: 11, volume: 20, anno: 2001,
pagine: 1563 - 1574
SICI:
0277-6715(20010615)20:11<1563:INBIRC>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
COST-EFFECTIVENESS ANALYSIS; MITOXANTRONE PLUS PREDNISONE; RESISTANT PROSTATE-CANCER; PALLIATIVE END-POINTS; CONFIDENCE-INTERVALS; EFFECTIVENESS RATIOS; ECONOMIC-EVALUATION; HEALTH-CARE; CHEMOTHERAPY; ESTIMATOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Willan, AR McMaster Univ, Dept Clin Epidemiol & Biostat, 600-143 James St S, Hamilton, ON L8P 3A1, Canada McMaster Univ 600-143 James St S Hamilton ON Canada L8P 3A1 ada
Citazione:
A.R. Willan e D.Y. Lin, "Incremental net benefit in randomized clinical trials", STAT MED, 20(11), 2001, pp. 1563-1574

Abstract

There are three approaches to health economic evaluation for comparing twotherapies. These are (i) cost minimization, in which one assumes or observes no difference in effectiveness, (ii) incremental cost-effectiveness, and(iii) incremental net benefit. The latter can be expressed either in unitsof effectiveness or costs. When analysing data from a clinical trial, expressing incremental net benefit in units of cost allows the investigator to examine all three approaches in a single graph, complete with the corresponding statistical inferences. Furthermore, if costs and effectiveness are not censored, this can be achieved using common two-sample statistical procedures. The above will be illustrated using two examples, one with censoring and one without. Copyright (C) 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:26:40