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Titolo:
Autoantibodies in cryptogenic fibrosing alveolitis
Autore:
Singh, S; du Bois, R;
Indirizzi:
Royal Brompton Hosp, London SW3 6NP, England Royal Brompton Hosp London England SW3 6NP Hosp, London SW3 6NP, England
Titolo Testata:
RESPIRATORY RESEARCH
fascicolo: 2, volume: 2, anno: 2001,
pagine: 61 - 63
SICI:
1465-993X(2001)2:2<61:AICFA>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
IDIOPATHIC PULMONARY FIBROSIS; EPSTEIN-BARR-VIRUS; CLINICAL RELEVANCE; IMMUNE-COMPLEXES; ASSOCIATION;
Keywords:
autoantibodies; cryptogenic fibrosing alveolitis; expression libraries; idiopathic pulmonary fibrosis; pathogenesis;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: du Bois, R Royal Brompton Hosp, Sydney St, London SW3 6NP, England Royal Brompton Hosp Sydney St London England SW3 6NP , England
Citazione:
S. Singh e R. du Bois, "Autoantibodies in cryptogenic fibrosing alveolitis", RESPIR RES, 2(2), 2001, pp. 61-63

Abstract

The pathogenesis of cryptogenic fibrosing alveolitis (CFA) involves injury, an immune/inflammatory response and fibrosis. The cause of the injury is unknown, but the identification of serum autoantibodies makes an autoimmuneaetiology attractive. The core study on which this commentary is based used novel cloning and serum screening technologies in order to identify new public and private autoantibodies in sera from 12 patients with CFA. Largelynegative conclusions were drawn from that study. However, we suggest that the prevalence of autoantibodies may have been underestimated, that the study was timely and that this approach is worth pursuing further.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:57:13