Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Recent advances in our understanding of human host responses to tuberculosis
Autore:
Schluger, NW;
Indirizzi:
Columbia Univ, Coll Phys & Surg, New York, NY USA Columbia Univ New York NY USA a Univ, Coll Phys & Surg, New York, NY USA
Titolo Testata:
RESPIRATORY RESEARCH
fascicolo: 3, volume: 2, anno: 2001,
pagine: 157 - 163
SICI:
1465-993X(2001)2:3<157:RAIOUO>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CD8(+) T-CELLS; VIRULENT MYCOBACTERIUM-TUBERCULOSIS; TUMOR-NECROSIS-FACTOR; TOLL-LIKE RECEPTORS; EXOGENOUS REINFECTION; NATURAL-RESISTANCE; HUMAN MACROPHAGES; INTERFERON-GAMMA; IMMUNE-RESPONSE; AVIUM COMPLEX;
Keywords:
CD4(+) cell; CD8(+) cell; immunity; interferon; tuberculosis;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: Schluger, NW Columbia Presbyterian Med Ctr, Div Pulm Allergy & Crit Care Med, PH-8 Ctr,630 W 168th St, New York, NY 10032 USA Columbia Presbyterian Med Ctr PH-8 Ctr,630 W 168th St New York NY USA 10032
Citazione:
N.W. Schluger, "Recent advances in our understanding of human host responses to tuberculosis", RESPIR RES, 2(3), 2001, pp. 157-163

Abstract

Tuberculosis remains one of the world's greatest public health challenges:2 billion persons have latent infection, 8 million people develop active tuberculosis annually, and 2-3 million die. Recently, significant advances in our understanding of the human immune response against tuberculosis have occurred. The present review focuses on recent work in macrophage and T-cell biology that sheds light on the human immune response to tuberculosis. The role of key cytokines such as interferon-gamma is discussed, as is the role of CD4(+) and CD8(+) T cells in immune regulation in tuberculosis, particularly with regard to implications for vaccine development and evaluation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 19:52:39