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Titolo:
Modelling cardiac mechanical properties in three dimensions
Autore:
Costa, KD; Holmes, JW; McCulloch, AD;
Indirizzi:
Columbia Univ, Dept Biomed Engn, New York, NY 10027 USA Columbia Univ NewYork NY USA 10027 t Biomed Engn, New York, NY 10027 USA Univ Calif San Diego, Dept Bioengn, Whitaker Inst Biomed Engn, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 d Engn, La Jolla, CA 92093 USA
Titolo Testata:
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
fascicolo: 1783, volume: 359, anno: 2001,
pagine: 1233 - 1250
SICI:
1364-503X(20010615)359:1783<1233:MCMPIT>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
CANINE LEFT-VENTRICLE; RAT LEFT-VENTRICLE; MUSCLE FORCE DEVELOPMENT; MYOCARDIAL-INFARCTION; PASSIVE MYOCARDIUM; TRANSMURAL DEFORMATION; CONSTITUTIVE RELATION; 3-DIMENSIONAL STRAIN; RESIDUAL STRAIN; STRESS;
Keywords:
myocardium; constitutive model; biaxial testing; mechanics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
71
Recensione:
Indirizzi per estratti:
Indirizzo: Costa, KD Columbia Univ, Dept Biomed Engn, MC 8904,530 W 120th St, New York, NY 10027 USA Columbia Univ MC 8904,530 W 120th St New York NY USA 10027 7 USA
Citazione:
K.D. Costa et al., "Modelling cardiac mechanical properties in three dimensions", PHI T ROY A, 359(1783), 2001, pp. 1233-1250

Abstract

The central problem in modelling the multi-dimensional mechanics of the heart is in identifying functional forms and parameters of the constitutive equations, which describe tile material properties of the resting and active, normal and diseased myocardium. The constitutive properties of myocardiumare three dimensional, anisotropic, nonlinear and time dependent. Formulating useful constitutive laws requires a combination of multi-axial tissue testing in. vitro, microstructural modelling based on quantitative morphology, statistical parameter estimation, and validation with measurements from intact hearts. Recent models capture some important properties of health;yrand diseased myocardium including: the nonlinear interactions between the responses to different loading patterns; the influence of the laminar myofibre sheet architecture; the effects of transverse stresses developed by themyocytes; and the relationship between collagen fibre architecture and mechanical properties in healing scar tissue after myocardial infarction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 08:25:00