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Titolo:
The architecture of the heart: a data-based model
Autore:
LeGrice, I; Hunter, P; Young, A; Small, B;
Indirizzi:
Univ Auckland, Sch Med, Dept Physiol, Auckland, New Zealand Univ AucklandAuckland New Zealand Dept Physiol, Auckland, New Zealand Univ Auckland, Dept Engn Sci, Sch Engn, Auckland, New Zealand Univ Auckland Auckland New Zealand Sci, Sch Engn, Auckland, New Zealand
Titolo Testata:
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
fascicolo: 1783, volume: 359, anno: 2001,
pagine: 1217 - 1232
SICI:
1364-503X(20010615)359:1783<1217:TAOTHA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONNECTIVE-TISSUE; PURKINJE-FIBERS; ATRIOVENTRICULAR NODE; COLLAGEN NETWORK; MUSCLE; MICROSCOPY; MORPHOLOGY; MYOCARDIUM; MECHANISMS; ISCHEMIA;
Keywords:
finite-element model; myocardial structure; fibrous laminar myocardium; geometry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: LeGrice, I Univ Auckland, Sch Med, Dept Physiol, Auckland, New Zealand Univ Auckland Auckland New Zealand ol, Auckland, New Zealand
Citazione:
I. LeGrice et al., "The architecture of the heart: a data-based model", PHI T ROY A, 359(1783), 2001, pp. 1217-1232

Abstract

An appropriate mathematical representation of heart structure is central to advancing an integrative approach to cardiac function. The Auckland heartmodel provides a realistic representation of important aspects of ventricular structure. The finite-element model is based on extensive anatomical data and incorporates detailed information on ventricular geometry and myocyte organization. It includes preliminary descriptions of the Purkinje fibre network, coronary vessels and collagen organization. Comprehensive extension of these data is required to exploit the full potential of computer modelling. In particular, we need to quantify the morphology of the atria, cardiac conduction system and the intramyocardial coronary vessels. This information must spall an appropriate range of species and disease states.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 13:13:23